POLA2 and FAM219A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POLA2	FAM219A
Description		DNA polymerase alpha 2, accessory subunit	family with sequence similarity 219 member A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Alpha DNA Polymerase:primase Complex Cytosol Ciliary Basal Body
	Molecular Function	DNA Binding Protein Binding	Protein Binding
	Biological Process	DNA Replication DNA Replication, Synthesis Of Primer DNA Replication Initiation Protein Import Into Nucleus
Pathways		Inhibition of replication initiation of damaged DNA by RB1/E2F1 Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation DNA replication initiation Activation of the pre-replicative complex Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand Defective pyroptosis
Drugs		Dacarbazine
Diseases
GWAS		Acne (severe) ( 24927181) Appendicular lean mass ( 33097823) Hip circumference adjusted for BMI ( 34021172) Serum uric acid levels ( 32514006)
Interacting Genes		33 interacting genes: AKTIP APP ASCC2 ATP5F1C CPE CRELD1 DCP2 DDX24 DHX34 EIF6 EZH2 FAM219A FGFR3 FRZB HDAC6 HELB HGH1 IGFBP3 KCNE3 KLF6 LRPAP1 MFHAS1 NR4A1 PARP1 POLA1 PRIM2 PRPF38A RBM23 SETDB1 SNU13 STK40 ULK2 XPNPEP1	8 interacting genes: CSNK1G1 LIMS3 LIMS4 NIPSNAP3A PDE6D POLA2 SPRY2 WWC1
Entrez ID		23649	203259
HPRD ID		10160	12950
Ensembl ID		ENSG00000014138	ENSG00000164970
Uniprot IDs		A0A9L9PY44 H0YDR7 Q14181	Q8IW50
PDB IDs		2KEB 4E2I 4Y97 5EXR 7OPL 7U5C 8B9D 8D0B 8D0K 8D9D 8QJ7 8VY3 9C8V
Enriched GO Terms of Interacting Partners?		DNA Replication, Synthesis Of Primer Regulation Of Phosphorus Metabolic Process Nucleic Acid Metabolic Process Collateral Sprouting RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Macromolecule Metabolic Process Alpha DNA Polymerase:primase Complex Regulation Of Glycolytic Process
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