MYCBP2 and ATP13A2

Number of citations of the paper that reports this interaction (PMID 22645275)
9

Data Source:
BioGRID (two hybrid)

		MYCBP2	ATP13A2
Gene Name		MYC binding protein 2, E3 ubiquitin protein ligase	ATPase type 13A2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Microtubule Cytoskeleton Membrane Axon	Lysosome Lysosomal Membrane Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Protein Homodimerization Activity	Protein Binding ATP Binding ATPase Activity Metal Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Regulation Of Protein Localization Negative Regulation Of Protein Catabolic Process Regulation Of Cytoskeleton Organization	Cation Transport Metabolic Process Cellular Response To Manganese Ion
Pathways
Drugs
Diseases
GWAS		Preeclampsia ( 23551011)	Height ( 20189936)
Protein-Protein Interactions		6 interactors: ATP13A2 CALM1 MYC PTPN12 YWHAG YWHAQ	36 interactors: ACKR3 ATP5G2 CCKBR CMTM6 COL1A1 CXCR4 CYGB DCAF7 EMC7 F2R FAM111B FAM192A FAM8A1 FKBP8 FUNDC2 GPR21 HIPK1 ICAM2 LMAN2 LRP6 MEX3B MYCBP2 NPY1R NRXN1 OCA2 OSTC PCDHB10 PCMTD2 PDIA6 SEC61B SPCS2 TSPAN14 UBE2J2 VAMP2 WDR5B WDR83OS
Entrez ID		23077	23400
HPRD ID		10104	13677
Ensembl ID		ENSG00000005810	ENSG00000159363
Uniprot IDs		J3KPZ3 O75592	Q9NQ11
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Substantia Nigra Development Neural Nucleus Development Positive Regulation Of Mitochondrion Organization Negative Regulation Of Phosphorylation Regulation Of Intracellular Transport Midbrain Development Cellular Response To Light Stimulus Regulation Of Mitochondrion Organization Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Fibroblast Apoptotic Process Energy Reserve Metabolic Process Intracellular Signal Transduction Cellular Response To Radiation Positive Regulation Of Transport Negative Regulation Of Cellular Metabolic Process Membrane Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Organelle Organization Cellular Response To Manganese Ion Regulation Of High Voltage-gated Calcium Channel Activity Apoptotic Process Programmed Cell Death Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Intracellular Transport Regulation Of Cellular Localization Cell Death Death Negative Regulation Of Monocyte Differentiation Positive Regulation Of Cell Proliferation Involved In Kidney Development Regulation Of Cell Division Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Transport Energy Derivation By Oxidation Of Organic Compounds Regulation Of Signal Transduction Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Protein Phosphorylation Response To Metal Ion Response To Light Stimulus Regulation Of Phosphorylation Detection Of Calcium Ion Apoptotic Signaling Pathway Regulation Of Cell Communication By Electrical Coupling	Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Protein Localization To Membrane Embryonic Retina Morphogenesis In Camera-type Eye Establishment Of Protein Localization To Membrane Regulation Of Signaling Establishment Of Protein Localization Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Localization Membrane Organization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cardiovascular System Development Synaptic Transmission Motor Neuron Axon Guidance Cell-cell Signaling Locomotion Positive Regulation Of Signal Transduction Chemotaxis Face Morphogenesis Embryonic Camera-type Eye Morphogenesis ER-associated Ubiquitin-dependent Protein Catabolic Process Head Morphogenesis Positive Regulation Of Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Canonical Wnt Signaling Pathway Involved In Cardiac Neural Crest Cell Differentiation Involved In Heart Development Negative Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure Negative Regulation Of Planar Cell Polarity Pathway Involved In Outflow Tract Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Pericardium Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Right Atrium Morphogenesis Negative Regulation Of Renin Secretion Into Blood Stream Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Muscle Tissue Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Ventricular Septum Morphogenesis Cellular Response To Fluoride Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Tyrosine Transport Synapse Organization Protein Localization To Nucleus Embryonic Eye Morphogenesis Cellular Protein Localization Regulation Of Protein Secretion Cellular Metal Ion Homeostasis Response To External Stimulus Cellular Homeostasis Cerebellum Morphogenesis Anatomical Structure Formation Involved In Morphogenesis Face Development Regulation Of Signal Transduction Cellular Protein Metabolic Process Regulation Of Insulin Secretion
Tagcloud ?		asd asds autism connectivity contributors deleterious fbxo45 hamartin idiopathic intronic mounting mtorc1 neurodevelopment pam pools proband representation resequenced rheb sanger simons splice synapse trios tsc tsc1 tsc2 tuberin variants	ataxin atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa lyst machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Difference) ?		asd asds autism connectivity contributors deleterious fbxo45 hamartin intronic mounting mtorc1 neurodevelopment pam pools proband representation resequenced rheb sanger simons splice synapse trios tsc tsc1 tsc2 tuberin variants	ataxin atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi joseph kufor levodopa lyst machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Intersection) ?		idiopathic