ATP13A2 and LMAN2

Number of citations of the paper that reports this interaction (PMID 22645275)
9

Data Source:
BioGRID (two hybrid)

		ATP13A2	LMAN2
Gene Name		ATPase type 13A2	lectin, mannose-binding 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Integral Component Of Membrane	Golgi Membrane Extracellular Space Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Integral Component Of Plasma Membrane Cell Surface Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ATP Binding ATPase Activity Metal Ion Binding	Glycoprotein Binding Mannose Binding Carbohydrate Binding Heat Shock Protein Binding Metal Ion Binding
	Biological Process	Cation Transport Metabolic Process Cellular Response To Manganese Ion	Retrograde Vesicle-mediated Transport, Golgi To ER Protein Transport Positive Regulation Of Phagocytosis
Pathways
Drugs
Diseases
GWAS		Height ( 20189936)	Activated partial thromboplastin time ( 22703881) Chronic kidney disease ( 20383146)
Protein-Protein Interactions		36 interactors: ACKR3 ATP5G2 CCKBR CMTM6 COL1A1 CXCR4 CYGB DCAF7 EMC7 F2R FAM111B FAM192A FAM8A1 FKBP8 FUNDC2 GPR21 HIPK1 ICAM2 LMAN2 LRP6 MEX3B MYCBP2 NPY1R NRXN1 OCA2 OSTC PCDHB10 PCMTD2 PDIA6 SEC61B SPCS2 TSPAN14 UBE2J2 VAMP2 WDR5B WDR83OS	4 interactors: ATP13A2 FRAT1 MAPK9 SUPT5H
Entrez ID		23400	10960
HPRD ID		13677	17285
Ensembl ID		ENSG00000159363	ENSG00000169223
Uniprot IDs		Q9NQ11	Q12907
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Protein Localization To Membrane Embryonic Retina Morphogenesis In Camera-type Eye Establishment Of Protein Localization To Membrane Regulation Of Signaling Establishment Of Protein Localization Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Localization Membrane Organization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cardiovascular System Development Synaptic Transmission Motor Neuron Axon Guidance Cell-cell Signaling Locomotion Positive Regulation Of Signal Transduction Chemotaxis Face Morphogenesis Embryonic Camera-type Eye Morphogenesis ER-associated Ubiquitin-dependent Protein Catabolic Process Head Morphogenesis Positive Regulation Of Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Canonical Wnt Signaling Pathway Involved In Cardiac Neural Crest Cell Differentiation Involved In Heart Development Negative Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure Negative Regulation Of Planar Cell Polarity Pathway Involved In Outflow Tract Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Pericardium Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Right Atrium Morphogenesis Negative Regulation Of Renin Secretion Into Blood Stream Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Muscle Tissue Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Ventricular Septum Morphogenesis Cellular Response To Fluoride Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Tyrosine Transport Synapse Organization Protein Localization To Nucleus Embryonic Eye Morphogenesis Cellular Protein Localization Regulation Of Protein Secretion Cellular Metal Ion Homeostasis Response To External Stimulus Cellular Homeostasis Cerebellum Morphogenesis Anatomical Structure Formation Involved In Morphogenesis Face Development Regulation Of Signal Transduction Cellular Protein Metabolic Process Regulation Of Insulin Secretion	Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Cellular Response To Manganese Ion JUN Phosphorylation Positive Regulation Of Prostaglandin Biosynthetic Process Response To Metal Ion Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Prostaglandin Secretion Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process Response To Inorganic Substance Positive Regulation Of Macroautophagy Response To Manganese Ion Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Icosanoid Secretion Positive Regulation Of Fatty Acid Transport Viral Genome Replication Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Macrophage Derived Foam Cell Differentiation Release Of Cytochrome C From Mitochondria Positive Regulation Of Fatty Acid Metabolic Process 7-methylguanosine MRNA Capping Regulation Of Fatty Acid Transport Regulation Of Fatty Acid Biosynthetic Process
Tagcloud ?		ataxin atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa lyst machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Difference) ?		ataxin atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa lyst machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Intersection) ?