ATP13A2 and ACKR3

Number of citations of the paper that reports this interaction (PMID 22645275)
9

Data Source:
BioGRID (two hybrid)

		ATP13A2	ACKR3
Gene Name		ATPase type 13A2	atypical chemokine receptor 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Integral Component Of Membrane	Endosome Early Endosome Plasma Membrane Coated Pit Cell Surface Integral Component Of Membrane Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Protein Binding ATP Binding ATPase Activity Metal Ion Binding	Scavenger Receptor Activity Protein Binding Coreceptor Activity C-X-C Chemokine Receptor Activity C-X-C Chemokine Binding
	Biological Process	Cation Transport Metabolic Process Cellular Response To Manganese Ion	Angiogenesis Vasculogenesis Chemotaxis Cell Adhesion G-protein Coupled Receptor Signaling Pathway Viral Process Receptor Internalization Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Height ( 20189936)
Protein-Protein Interactions		36 interactors: ACKR3 ATP5G2 CCKBR CMTM6 COL1A1 CXCR4 CYGB DCAF7 EMC7 F2R FAM111B FAM192A FAM8A1 FKBP8 FUNDC2 GPR21 HIPK1 ICAM2 LMAN2 LRP6 MEX3B MYCBP2 NPY1R NRXN1 OCA2 OSTC PCDHB10 PCMTD2 PDIA6 SEC61B SPCS2 TSPAN14 UBE2J2 VAMP2 WDR5B WDR83OS	1 interactors: ATP13A2
Entrez ID		23400	57007
HPRD ID		13677	09882
Ensembl ID		ENSG00000159363	ENSG00000144476
Uniprot IDs		Q9NQ11	P25106
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Protein Localization To Membrane Embryonic Retina Morphogenesis In Camera-type Eye Establishment Of Protein Localization To Membrane Regulation Of Signaling Establishment Of Protein Localization Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Localization Membrane Organization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cardiovascular System Development Synaptic Transmission Motor Neuron Axon Guidance Cell-cell Signaling Locomotion Positive Regulation Of Signal Transduction Chemotaxis Face Morphogenesis Embryonic Camera-type Eye Morphogenesis ER-associated Ubiquitin-dependent Protein Catabolic Process Head Morphogenesis Positive Regulation Of Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Canonical Wnt Signaling Pathway Involved In Cardiac Neural Crest Cell Differentiation Involved In Heart Development Negative Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure Negative Regulation Of Planar Cell Polarity Pathway Involved In Outflow Tract Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Pericardium Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Right Atrium Morphogenesis Negative Regulation Of Renin Secretion Into Blood Stream Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Muscle Tissue Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Ventricular Septum Morphogenesis Cellular Response To Fluoride Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Tyrosine Transport Synapse Organization Protein Localization To Nucleus Embryonic Eye Morphogenesis Cellular Protein Localization Regulation Of Protein Secretion Cellular Metal Ion Homeostasis Response To External Stimulus Cellular Homeostasis Cerebellum Morphogenesis Anatomical Structure Formation Involved In Morphogenesis Face Development Regulation Of Signal Transduction Cellular Protein Metabolic Process Regulation Of Insulin Secretion	Cellular Response To Manganese Ion Response To Manganese Ion Cellular Response To Metal Ion Cellular Response To Inorganic Substance Response To Metal Ion
Tagcloud ?		ataxin atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa lyst machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Difference) ?		ataxin atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa lyst machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Intersection) ?