MYCBP2 and PABPN1

Number of citations of the paper that reports this interaction (PubMedID 21653829)
54

Data Source:
BioGRID (two hybrid)

		MYCBP2	PABPN1
Description		MYC binding protein 2	poly(A) binding protein nuclear 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Membrane Axon Cell Projection	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Nuclear Inclusion Body Ribonucleoprotein Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Transferase Activity Small GTPase Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Nucleic Acid Binding RNA Binding Protein Binding Poly(A) Binding RNA Polymerase Binding
	Biological Process	Axon Guidance Motor Neuron Axon Guidance Regulation Of Synaptic Assembly At Neuromuscular Junction Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Rhythmic Process Cell Morphogenesis Involved In Neuron Differentiation Neuromuscular Process Regulation Of Cytoskeleton Organization Axon Development Protein K48-linked Ubiquitination Regulation Of Axon Guidance	MAPK Cascade RNA Processing MRNA Processing Muscle Contraction Poly(A)+ MRNA Export From Nucleus Cellular Response To Lipopolysaccharide Positive Regulation Of Polynucleotide Adenylyltransferase Activity
Pathways			Inhibition of Host mRNA Processing and RNA Silencing mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs Z-decay: degradation of maternal mRNAs by zygotically expressed factors Nuclear RNA decay
Drugs
Diseases			Oculopharyngeal muscular dystrophy (OPMD)
GWAS		Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Appendicular lean mass ( 33097823) Body mass index ( 26865924) Lymphocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		50 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 BTG3 CALM1 CD81 CEBPA CFL1 CUEDC2 DHRS4L2 DSCR9 DYRK1A ERBB3 FHL3 FSCN1 HSP90AB1 HUNK IGFBP6 LCOR LDHB LSM14A MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 RSPH1 SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ	15 interacting genes: CARM1 DNAJB4 HNRNPA1 HSP90AA1 IL7R LATS1 LINC00839 MYCBP2 OGT PRMT3 SMARCA4 SNW1 STAU1 TNPO1 YWHAQ
Entrez ID		23077	8106
HPRD ID		10104	03787
Ensembl ID		ENSG00000005810	ENSG00000100836
Uniprot IDs		O75592	G3V4T2 Q86U42
PDB IDs		5O6C 6T7F	3B4D 3B4M 3UCG
Enriched GO Terms of Interacting Partners?		Cytoplasm Intracellular Signal Transduction	Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Protein Ubiquitination Protein-containing Complex Regulation Of Post-translational Protein Modification Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Protein-arginine N-methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Regulation Of Gene Expression Positive Regulation Of Developmental Process Positive Regulation Of Cell Differentiation Regulation Of Developmental Process Regulation Of Macromolecule Biosynthetic Process Host-mediated Activation Of Viral Transcription Regulation Of Primary Metabolic Process Regulation Of Metabolic Process DNA Polymerase Binding Positive Regulation Of Telomere Maintenance Via Telomerase Regulation Of Protein Modification Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Transmembrane Transporter Binding Nuclear Androgen Receptor Binding Host-mediated Perturbation Of Viral Transcription Positive Regulation Of Transcription By RNA Polymerase I Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Cytosol Regulation Of Synapse Assembly Histone Methyltransferase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Host-mediated Activation Of Viral Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Cell Communication Positive Regulation Of Signaling Cell Morphogenesis Positive Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase I Regulation Of Telomere Maintenance Via Telomerase Regulation Of Cellular Component Organization Nucleoplasm Positive Regulation Of DNA Biosynthetic Process Regulation Of DNA Metabolic Process CTP Binding DATP Binding Positive Regulation Of Stem Cell Population Maintenance Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Macromolecule Biosynthetic Process
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