MYCBP2 and CUEDC2

Number of citations of the paper that reports this interaction (PubMedID 21653829)
54

Data Source:
BioGRID (two hybrid)

		MYCBP2	CUEDC2
Description		MYC binding protein 2	CUE domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Membrane Axon Cell Projection	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Transferase Activity Small GTPase Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Ubiquitin Binding
	Biological Process	Axon Guidance Motor Neuron Axon Guidance Regulation Of Synaptic Assembly At Neuromuscular Junction Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Rhythmic Process Cell Morphogenesis Involved In Neuron Differentiation Neuromuscular Process Regulation Of Cytoskeleton Organization Axon Development Protein K48-linked Ubiquitination Regulation Of Axon Guidance	Negative Regulation Of Macrophage Cytokine Production Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Autism spectrum disorder-related traits ( 25534755) Prostate cancer ( 23535732) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		50 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 BTG3 CALM1 CD81 CEBPA CFL1 CUEDC2 DHRS4L2 DSCR9 DYRK1A ERBB3 FHL3 FSCN1 HSP90AB1 HUNK IGFBP6 LCOR LDHB LSM14A MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 RSPH1 SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ	12 interacting genes: AGTR1 CHUK ESR1 EWSR1 IKBKB MAPK1 MAPK3 MYCBP2 PGR SOCS1 SOCS3 UBC
Entrez ID		23077	79004
HPRD ID		10104	13099
Ensembl ID		ENSG00000005810	ENSG00000107874
Uniprot IDs		O75592	Q9H467
PDB IDs		5O6C 6T7F
Enriched GO Terms of Interacting Partners?		Cytoplasm Intracellular Signal Transduction	Regulation Of Defense Response Intracellular Signal Transduction Cytokine-mediated Signaling Pathway Cellular Response To Tumor Necrosis Factor Stress-activated Protein Kinase Signaling Cascade Stress-activated MAPK Cascade Response To Tumor Necrosis Factor IkappaB Kinase Activity Interleukin-34-mediated Signaling Pathway Regulation Of Golgi Inheritance Phosphotyrosine Residue Binding Caveolin-mediated Endocytosis Positive Regulation Of Macrophage Proliferation Regulation Of Inflammatory Response Cellular Response To Cytokine Stimulus IkappaB Kinase Complex Cardiac Neural Crest Cell Development Involved In Heart Development Trachea Formation Positive Regulation Of Defense Response Outer Ear Morphogenesis ERBB3 Signaling Pathway ERBB2-ERBB3 Signaling Pathway Bergmann Glial Cell Differentiation CD40 Receptor Complex Transferrin Receptor Binding Estrogen Response Element Binding Response To Cytokine Response To Peptide Protein Ubiquitination Mammary Gland Epithelial Cell Proliferation MAP Kinase Activity Cytoplasmic Side Of Plasma Membrane Protein Modification Process Regulation Of Golgi Organization Pseudopodium Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Early Endosome To Late Endosome Transport Schwann Cell Development Protein Modification By Small Protein Conjugation Positive Regulation Of Macrophage Chemotaxis Positive Regulation Of Neuroinflammatory Response Animal Organ Formation Nuclear Steroid Receptor Activity Identical Protein Binding Face Development Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT ERBB2 Signaling Pathway Protein Serine/threonine Kinase Activity Interleukin-1-mediated Signaling Pathway Positive Regulation Of Macrophage Migration
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