MYCBP2 and PRXL2A

Number of citations of the paper that reports this interaction (PubMedID 21653829)
54

Data Source:
BioGRID (two hybrid)

		MYCBP2	PRXL2A
Description		MYC binding protein 2	peroxiredoxin like 2A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Membrane Axon Cell Projection	Extracellular Region Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Transferase Activity Small GTPase Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Antioxidant Activity
	Biological Process	Axon Guidance Motor Neuron Axon Guidance Regulation Of Synaptic Assembly At Neuromuscular Junction Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Rhythmic Process Cell Morphogenesis Involved In Neuron Differentiation Neuromuscular Process Regulation Of Cytoskeleton Organization Axon Development Protein K48-linked Ubiquitination Regulation Of Axon Guidance	Regulation Of Osteoclast Differentiation Cellular Oxidant Detoxification
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		50 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 BTG3 CALM1 CD81 CEBPA CFL1 CUEDC2 DHRS4L2 DSCR9 DYRK1A ERBB3 FHL3 FSCN1 HSP90AB1 HUNK IGFBP6 LCOR LDHB LSM14A MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 RSPH1 SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ	2 interacting genes: APP MYCBP2
Entrez ID		23077	84293
HPRD ID		10104	12580
Ensembl ID		ENSG00000005810	ENSG00000122378
Uniprot IDs		O75592	Q9BRX8
PDB IDs		5O6C 6T7F
Enriched GO Terms of Interacting Partners?		Cytoplasm Intracellular Signal Transduction	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Cell Junction Assembly Cell Projection Morphogenesis Regulation Of Synapse Assembly Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Synapse Organization Regulation Of Response To Calcium Ion Regulation Of Developmental Growth Regulation Of Chemotaxis Amylin Binding Neuron Projection Morphogenesis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Axonogenesis Axon Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Regulation Of Protein Catabolic Process Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Neuron Projection Development Axon Choice Point Recognition Branchiomotor Neuron Axon Guidance Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Regulation Of Synaptic Assembly At Neuromuscular Junction Regulation Of Growth
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