MYCBP2 and RGPD8

Number of citations of the paper that reports this interaction (PubMedID 21653829)
54

Data Source:
BioGRID (two hybrid)

		MYCBP2	RGPD8
Description		MYC binding protein 2	RANBP2 like and GRIP domain containing 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Membrane Axon Cell Projection	Nuclear Pore Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Transferase Activity Small GTPase Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	GTPase Activator Activity Small GTPase Binding
	Biological Process	Axon Guidance Motor Neuron Axon Guidance Regulation Of Synaptic Assembly At Neuromuscular Junction Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Rhythmic Process Cell Morphogenesis Involved In Neuron Differentiation Neuromuscular Process Regulation Of Cytoskeleton Organization Axon Development Protein K48-linked Ubiquitination Regulation Of Axon Guidance	NLS-bearing Protein Import Into Nucleus
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		50 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 BTG3 CALM1 CD81 CEBPA CFL1 CUEDC2 DHRS4L2 DSCR9 DYRK1A ERBB3 FHL3 FSCN1 HSP90AB1 HUNK IGFBP6 LCOR LDHB LSM14A MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 RSPH1 SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ	2 interacting genes: MYCBP2 USP7
Entrez ID		23077	727851
HPRD ID		10104
Ensembl ID		ENSG00000005810	ENSG00000169629
Uniprot IDs		O75592	F8W705 O14715
PDB IDs		5O6C 6T7F
Enriched GO Terms of Interacting Partners?		Cytoplasm Intracellular Signal Transduction	Negative Regulation Of Protein Catabolic Process Rhythmic Process Regulation Of Protein Catabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Catabolic Process Regulation Of Establishment Of Protein Localization To Chromosome Monoubiquitinated Protein Deubiquitination Regulation Of Establishment Of Protein Localization To Telomere DNA Alkylation Repair Regulation Of Retrograde Transport, Endosome To Golgi Transcription-coupled Nucleotide-excision Repair Protein Ubiquitination Negative Regulation Of Protein Metabolic Process Branchiomotor Neuron Axon Guidance Regulation Of Axon Guidance Regulation Of Synaptic Assembly At Neuromuscular Junction Protein Modification By Small Protein Conjugation Regulation Of Telomere Capping Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation K48-linked Deubiquitinase Activity Negative Regulation Of Gluconeogenesis Post-translational Protein Modification Cell Morphogenesis Involved In Neuron Differentiation Deubiquitinase Activity Regulation Of Protein Localization Central Nervous System Projection Neuron Axonogenesis Motor Neuron Axon Guidance Central Nervous System Neuron Axonogenesis Regulation Of Organelle Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleotide-excision Repair Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of TORC1 Signaling Regulation Of Gluconeogenesis Negative Regulation Of Proteasomal Protein Catabolic Process TORC1 Signaling Cysteine-type Endopeptidase Activity Regulation Of Protein Metabolic Process Circadian Regulation Of Gene Expression Axon Development P53 Binding Protein Modification Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process TOR Signaling Negative Regulation Of Autophagy Negative Regulation Of Small Molecule Metabolic Process Cysteine-type Deubiquitinase Activity Autophagosome Organization Protein Deubiquitination Protein Modification By Small Protein Removal
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