HECW1 and USP7

  • Number of citations of the paper that reports this interaction (PMID 16713569)
  • 214

HECW1

USP7

Gene Name HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 ubiquitin specific peptidase 7 (herpes virus-associated)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (cognitive decline) ( 23535033)
  • Obesity-related traits ( 23251661)
Protein-Protein Interactions 10 interactors: CACNA1A DVL1 GFI1B SCNN1A SCNN1B SSR4 TNK2 TP53 UBC USP7 85 interactors: ACD ARNT2 ATXN1 BCOR BEND5 BMI1 CBX8 CHEK1 CLSPN CREB3L3 DAXX DNAJA3 DNMT1 DNMT3A EWSR1 EZH2 FAM175B FOXN2 HECW1 HERPUD1 HIST3H2BB HTRA2 KAT5 KLHL8 MAGEE1 MAL MARCH7 MCMBP MDM2 MDM4 MYD88 NECAB2 PCGF2 PEG3 PEPD PHLDB2 PICK1 PJA1 PLA2G2A PLEKHO1 PPARG PPL RADIL RARA RB1 RBCK1 RELA RFFL RING1 RNF2 RNF220 SMAD3 SUMO1 SUZ12 SYVN1 TANK TBCB TMPO TP53 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TRIM22 TRIM27 TRIM31 TRIM54 TRIM55 TRIM63 TRIM8 TRO UBC UBE2E1 UBE2S UHRF2 USP15 USP21 USP28 WWP2 XPC ZEB1 ZMYND8 ZNF423
Entrez ID 23072 7874
HPRD ID 11385 03950
Ensembl ID ENSG00000187555
Uniprot IDs B4DH42 Q76N89 B7Z815 Q6U8A4 Q93009
PDB IDs 3L4H 1NB8 1NBF 1YY6 1YZE 2F1W 2F1X 2F1Y 2F1Z 2FOJ 2FOO 2FOP 2KVR 2XXN 2YLM 3MQR 3MQS 4JJQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accordingly  adenocarcinoma  bad  carcinoma  clarified  de  downregulation  excluding  h460  hbe  indicator  invasion  invasive  mdm2  mesenchymal  metastasis  nsclc  overexpression  preliminary  regulate  serve  squamous  stabilization  tumorous  ubiquitination  upregulation  usp7high  usp7low  vshrna 
Tagcloud (Difference) ?
accordingly  adenocarcinoma  bad  carcinoma  clarified  de  downregulation  excluding  h460  hbe  indicator  invasion  invasive  mdm2  mesenchymal  metastasis  nsclc  overexpression  preliminary  regulate  serve  squamous  stabilization  tumorous  ubiquitination  upregulation  usp7high  usp7low  vshrna 
Tagcloud (Intersection) ?