HECW1 and CACNA1A

  • Number of citations of the paper that reports this interaction (PMID 21078624)
  • 14
  • Data Source:
  • BioGRID (two hybrid)

HECW1

CACNA1A

Gene Name HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (cognitive decline) ( 23535033)
  • Obesity-related traits ( 23251661)
Protein-Protein Interactions 10 interactors: CACNA1A DVL1 GFI1B SCNN1A SCNN1B SSR4 TNK2 TP53 UBC USP7 92 interactors: ABCA2 ABI1 ACTN1 AGRN ALDOA AMIGO2 AP2M1 ARHGAP22 ASNA1 BTG3 BZRAP1 C1QTNF1 CABP1 CACNB1 CACNB4 CALM2 CALM3 CKAP5 CRIM1 CRMP1 CSNK2B CYSRT1 DNAJB5 EFEMP1 EFEMP2 EHMT2 EIF3A FBLN1 GNB1 GOLGA6L5P GRN HECW1 HHATL HIVEP1 HSPG2 IP6K1 JAG2 KALRN KHDRBS3 KIAA1191 LAMB1 LLGL1 LPHN1 LRP1 LTBP1 LTBP3 LTBP4 MANBAL MATK MATN2 MEGF6 MEGF8 MIA3 MOAP1 NDUFB8 NELFCD NELL1 NELL2 NOTCH1 NOXA1 OLIG1 PCSK5 PCSK6 PMM1 PPIG PPM1A PPP1R12C PTGDS PUF60 RBM12B RIMBP2 RPL31 RPS17 SCP2 SPRY1 SRRM4 SRSF1 SUMF2 SYT1 TAF15 TELO2 TSC22D1 TSPAN7 TUBB2B UQCRC2 VARS VPS52 VWF WBP1 YLPM1 ZCCHC17 ZNF233
Entrez ID 23072 773
HPRD ID 11385 03004
Ensembl ID ENSG00000141837
Uniprot IDs B4DH42 Q76N89 B5TYJ1 O00555 Q9NS89
PDB IDs 3L4H 3BXK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acetazolamide  ataxia  attacks  autosomal  causative  causing  coincidence  confutes  defect  dysarthria  dystonia  ea  ea2  encodes  episodes  episodic  gait  gated  heterogeneous  inherited  migraine  mim  nonsense  oculomotor  paroxysmal  q  varied  voltage 
Tagcloud (Difference) ?
acetazolamide  ataxia  attacks  autosomal  causative  causing  coincidence  confutes  defect  dysarthria  dystonia  ea  ea2  encodes  episodes  episodic  gait  gated  heterogeneous  inherited  migraine  mim  nonsense  oculomotor  paroxysmal  q  varied  voltage 
Tagcloud (Intersection) ?