CNKSR2 and LRRC7

Number of citations of the paper that reports this interaction (PMID 12390249)
7

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		CNKSR2	LRRC7
Gene Name		connector enhancer of kinase suppressor of Ras 2	leucine rich repeat containing 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Neuron Projection Neuronal Cell Body Postsynaptic Membrane Extracellular Vesicular Exosome	Cytoplasm Postsynaptic Density Cell Junction Postsynaptic Membrane
	Molecular Function	Identical Protein Binding	Protein Binding
	Biological Process	Regulation Of Signal Transduction
Pathways
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 21784300) Hypertension risk in short sleep duration ( 22322875) Obesity-related traits ( 23251661) Orofacial clefts ( 22419666)
Protein-Protein Interactions		12 interactors: DLG1 DLG2 DLG3 DLG4 INADL LRRC7 RALA RGS3 SHANK3 SNTA1 TJP1 TNIK	11 interactors: ACTN2 ACTN4 BAI1 CAMK2A CAMK2G CDH2 CNKSR2 CTNND2 HOMEZ NQO2 TOR1A
Entrez ID		22866	57554
HPRD ID		06473	09930
Ensembl ID		ENSG00000149970	ENSG00000033122
Uniprot IDs		B3KPN2 Q8WXI2	Q96NW7
PDB IDs		2EAN 3BS5
Enriched GO Terms of Interacting Partners?		Receptor Localization To Synapse Receptor Clustering Protein Localization To Synapse Membrane Organization Protein Localization To Membrane Nucleotide Phosphorylation Establishment Or Maintenance Of Apical/basal Cell Polarity Cell-cell Signaling Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Synaptic Transmission Regulation Of Membrane Potential Dendritic Spine Morphogenesis Cellular Protein Localization Vocalization Behavior Cell-cell Junction Assembly Cellular Localization Dendritic Spine Development Regulation Of Ion Transmembrane Transport Dendritic Spine Organization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Synapse Organization Cortical Actin Cytoskeleton Organization Response To External Stimulus Postsynaptic Membrane Organization Establishment Or Maintenance Of Cell Polarity Phosphorylation Cortical Cytoskeleton Organization Signaling Cellular Component Assembly Regulation Of Long-term Neuronal Synaptic Plasticity Protein Localization Cytoskeleton Organization Nucleotide Metabolic Process Cell Junction Assembly Cell Communication Cell Projection Organization Positive Regulation Of Excitatory Postsynaptic Membrane Potential Cell Morphogenesis Involved In Neuron Differentiation Cell-cell Junction Organization Chemotaxis Actin Cytoskeleton Organization Regulation Of Sodium Ion Transmembrane Transport Regulation Of Ion Transport Neuron Projection Morphogenesis Social Behavior Actin Filament-based Process Nucleobase-containing Small Molecule Metabolic Process Positive Regulation Of Membrane Potential Tight Junction Assembly Cell Morphogenesis Involved In Differentiation	Regulation Of Ion Transport Regulation Of Protein Localization To Cell Surface Regulation Of Cellular Response To Heat Positive Regulation Of Ion Transport Cell Junction Assembly Cell-cell Junction Organization Synaptic Transmission Cell Adhesion Positive Regulation Of Transport Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Synaptic Transmission Cellular Response To Heat Platelet Degranulation Cell-cell Signaling Positive Regulation Of Ion Transmembrane Transport Adherens Junction Organization Protein Oligomerization Cellular Component Assembly Positive Regulation Of Endocytosis Regulation Of Signaling Response To Heat Establishment Of Localization In Cell Protein Localization To Tight Junction Positive Regulation Of Synaptic Vesicle Endocytosis Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Pinocytosis ER-associated Misfolded Protein Catabolic Process Secretion By Cell Interferon-gamma-mediated Signaling Pathway Positive Regulation Of Sodium:proton Antiporter Activity Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cellular Response To Interferon-gamma Nuclear Membrane Organization Wound Healing G1/S Transition Of Mitotic Cell Cycle Regulation Of Synaptic Plasticity Regulation Of Synaptic Vesicle Endocytosis Regulation Of Sodium:proton Antiporter Activity Microspike Assembly Peroxisome Proliferator Activated Receptor Signaling Pathway Secretion Response To Interferon-gamma Cellular Localization Regulation Of Relaxation Of Cardiac Muscle Regulation Of Endocytosis Response To Temperature Stimulus Regulation Of Calcium Ion Transport Response To Wounding
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