ACIN1 and PCBD1

Number of citations of the paper that reports this interaction (PMID 20195357)
18

Data Source:
BioGRID (pull down)

		ACIN1	PCBD1
Gene Name		apoptotic chromatin condensation inducer 1	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Nuclear Speck Exon-exon Junction Complex ASAP Complex	Nucleoplasm Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding Nucleic Acid Binding Protein Binding ATPase Activity Enzyme Binding Poly(A) RNA Binding	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding
	Biological Process	MRNA Processing Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis RNA Splicing Erythrocyte Differentiation Apoptotic Chromosome Condensation Positive Regulation Of Apoptotic Process Positive Regulation Of Monocyte Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome	Transcription, DNA-templated L-phenylalanine Catabolic Process Tetrahydrobiopterin Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Homodimerization Activity Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated Protein Homotetramerization Protein Heterooligomerization Oxidation-reduction Process
Pathways		Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase	Phenylalanine and tyrosine catabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		11 interactors: ABCF3 AKR1C3 BTBD10 CASP3 CSNK2A1 KLHL26 PAFAH1B2 PCBD1 RNPS1 SRPK2 YWHAG	49 interactors: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF1B HNF4A KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NUDT18 PAH PAPOLG PCBD2 POLR3A RBL2 RPS24 SAP30 SCMH1 SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WDYHV1 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF714
Entrez ID		22985	5092
HPRD ID		05191	00523
Ensembl ID		ENSG00000100813	ENSG00000166228
Uniprot IDs		B4DQZ7 Q9UKV3	P61457
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Apoptotic Process Positive Regulation Of Metabolic Process Regulation Of Neuron Death Regulation Of Metabolic Process Positive Regulation Of Neuron Apoptotic Process Regulation Of MRNA Splicing, Via Spliceosome Nuclear Speck Organization Negative Regulation Of Retinoic Acid Biosynthetic Process Catabolic Process Positive Regulation Of Neuron Death Regulation Of MRNA Processing Keratinocyte Differentiation Aromatic Compound Catabolic Process Regulation Of RNA Splicing Regulation Of Testosterone Biosynthetic Process Farnesol Catabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Isoprenoid Metabolic Process Sesquiterpenoid Metabolic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Epidermal Cell Differentiation Cellular Response To Jasmonic Acid Stimulus Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Cellular Response To Prostaglandin D Stimulus Intrinsic Apoptotic Signaling Pathway Glial Cell Apoptotic Process Cellular Response To Oxidative Stress Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process System Development Regulation Of Apoptotic DNA Fragmentation Daunorubicin Metabolic Process Doxorubicin Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Protein Kinase Activity Testosterone Biosynthetic Process Negative Regulation Of Catalytic Activity Skin Development Negative Regulation Of Cellular Protein Metabolic Process Tetrahydrobiopterin Biosynthetic Process MRNA Splicing, Via Spliceosome Negative Regulation Of Kinase Activity Positive Regulation Of Cell Proliferation RNA Splicing, Via Transesterification Reactions Regulation Of Neuron Apoptotic Process Lipid Catabolic Process	RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Gene Expression Heterocycle Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Metabolic Process Chromatin Remodeling Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Chromatin Organization Insulin Secretion Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Chromosome Organization Chromatin Modification Endocrine Pancreas Development Regulation Of Cellular Process Peptide Hormone Secretion Peptide Secretion Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Cellular Process Positive Regulation Of DNA-templated Transcription, Initiation Hormone Secretion
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