ACIN1 and ABCF3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ACIN1	ABCF3
Gene Name		apoptotic chromatin condensation inducer 1	ATP-binding cassette, sub-family F (GCN20), member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Nuclear Speck Exon-exon Junction Complex ASAP Complex	Membrane
	Molecular Function	Nucleotide Binding Nucleic Acid Binding Protein Binding ATPase Activity Enzyme Binding Poly(A) RNA Binding	ATP Binding ATPase Activity
	Biological Process	MRNA Processing Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis RNA Splicing Erythrocyte Differentiation Apoptotic Chromosome Condensation Positive Regulation Of Apoptotic Process Positive Regulation Of Monocyte Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome	Metabolic Process Defense Response To Virus
Pathways		Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS			Major depressive disorder ( 22472876)
Protein-Protein Interactions		11 interactors: ABCF3 AKR1C3 BTBD10 CASP3 CSNK2A1 KLHL26 PAFAH1B2 PCBD1 RNPS1 SRPK2 YWHAG	14 interactors: ACIN1 CCDC33 DLEU1 DNALI1 FCHSD2 HIRIP3 LAMTOR1 MOCS2 NOA1 SLC35E1 SPP1 TBPL1 TOE1 TRIM27
Entrez ID		22985	55324
HPRD ID		05191	12404
Ensembl ID		ENSG00000100813	ENSG00000161204
Uniprot IDs		B4DQZ7 Q9UKV3	Q9NUQ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Apoptotic Process Positive Regulation Of Metabolic Process Regulation Of Neuron Death Regulation Of Metabolic Process Positive Regulation Of Neuron Apoptotic Process Regulation Of MRNA Splicing, Via Spliceosome Nuclear Speck Organization Negative Regulation Of Retinoic Acid Biosynthetic Process Catabolic Process Positive Regulation Of Neuron Death Regulation Of MRNA Processing Keratinocyte Differentiation Aromatic Compound Catabolic Process Regulation Of RNA Splicing Regulation Of Testosterone Biosynthetic Process Farnesol Catabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Isoprenoid Metabolic Process Sesquiterpenoid Metabolic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Epidermal Cell Differentiation Cellular Response To Jasmonic Acid Stimulus Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Cellular Response To Prostaglandin D Stimulus Intrinsic Apoptotic Signaling Pathway Glial Cell Apoptotic Process Cellular Response To Oxidative Stress Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process System Development Regulation Of Apoptotic DNA Fragmentation Daunorubicin Metabolic Process Doxorubicin Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Protein Kinase Activity Testosterone Biosynthetic Process Negative Regulation Of Catalytic Activity Skin Development Negative Regulation Of Cellular Protein Metabolic Process Tetrahydrobiopterin Biosynthetic Process MRNA Splicing, Via Spliceosome Negative Regulation Of Kinase Activity Positive Regulation Of Cell Proliferation RNA Splicing, Via Transesterification Reactions Regulation Of Neuron Apoptotic Process Lipid Catabolic Process	Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Reproduction Organelle Organization Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Negative Regulation Of Interleukin-2 Secretion Single Organism Reproductive Process Endosome Localization Regulation Of Cholesterol Import Reproductive Process DTTP Biosynthetic Process Apoptotic Chromosome Condensation Negative Regulation Of Calcium Ion Import Positive Regulation Of Monocyte Differentiation Negative Regulation Of Collateral Sprouting
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