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ACIN1 and PAFAH1B2
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
ACIN1
PAFAH1B2
Gene Name
apoptotic chromatin condensation inducer 1
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Nuclear Speck
Exon-exon Junction Complex
ASAP Complex
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Extracellular Vesicular Exosome
Molecular Function
Nucleotide Binding
Nucleic Acid Binding
Protein Binding
ATPase Activity
Enzyme Binding
Poly(A) RNA Binding
1-alkyl-2-acetylglycerophosphocholine Esterase Activity
Protein Homodimerization Activity
Protein Heterodimerization Activity
Platelet-activating Factor Acetyltransferase Activity
Biological Process
MRNA Processing
Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
RNA Splicing
Erythrocyte Differentiation
Apoptotic Chromosome Condensation
Positive Regulation Of Apoptotic Process
Positive Regulation Of Monocyte Differentiation
Negative Regulation Of MRNA Splicing, Via Spliceosome
Lipid Metabolic Process
Spermatogenesis
Brain Development
Lipid Catabolic Process
Positive Regulation Of Macroautophagy
Pathways
Apoptotic cleavage of cellular proteins
Programmed Cell Death
Apoptotic execution phase
Drugs
Diseases
GWAS
Protein quantitative trait loci (
18464913
)
Protein-Protein Interactions
11 interactors:
ABCF3
AKR1C3
BTBD10
CASP3
CSNK2A1
KLHL26
PAFAH1B2
PCBD1
RNPS1
SRPK2
YWHAG
14 interactors:
ACIN1
ASF1A
CCT3
PAFAH1B1
PAFAH1B3
PARK2
PINX1
PPP1R12C
REXO1
RPLP0
SLA
SNUPN
TIMM50
ZFP36L1
Entrez ID
22985
5049
HPRD ID
05191
03940
Ensembl ID
ENSG00000100813
ENSG00000168092
Uniprot IDs
B4DQZ7
Q9UKV3
P68402
PDB IDs
1VYH
Enriched GO Terms of Interacting Partners
?
Regulation Of Cell Death
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Regulation Of Apoptotic Process
Positive Regulation Of Metabolic Process
Regulation Of Neuron Death
Regulation Of Metabolic Process
Positive Regulation Of Neuron Apoptotic Process
Regulation Of MRNA Splicing, Via Spliceosome
Nuclear Speck Organization
Negative Regulation Of Retinoic Acid Biosynthetic Process
Catabolic Process
Positive Regulation Of Neuron Death
Regulation Of MRNA Processing
Keratinocyte Differentiation
Aromatic Compound Catabolic Process
Regulation Of RNA Splicing
Regulation Of Testosterone Biosynthetic Process
Farnesol Catabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Isoprenoid Metabolic Process
Sesquiterpenoid Metabolic Process
Negative Regulation Of Protein Serine/threonine Kinase Activity
Epidermal Cell Differentiation
Cellular Response To Jasmonic Acid Stimulus
Regulation Of Cell Proliferation
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Prostaglandin D Stimulus
Intrinsic Apoptotic Signaling Pathway
Glial Cell Apoptotic Process
Cellular Response To Oxidative Stress
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
System Development
Regulation Of Apoptotic DNA Fragmentation
Daunorubicin Metabolic Process
Doxorubicin Metabolic Process
Regulation Of Cysteine-type Endopeptidase Activity
Negative Regulation Of Protein Kinase Activity
Testosterone Biosynthetic Process
Negative Regulation Of Catalytic Activity
Skin Development
Negative Regulation Of Cellular Protein Metabolic Process
Tetrahydrobiopterin Biosynthetic Process
MRNA Splicing, Via Spliceosome
Negative Regulation Of Kinase Activity
Positive Regulation Of Cell Proliferation
RNA Splicing, Via Transesterification Reactions
Regulation Of Neuron Apoptotic Process
Lipid Catabolic Process
Positive Regulation Of Cytokine-mediated Signaling Pathway
Positive Regulation Of Response To Cytokine Stimulus
Protein Localization To Organelle
Negative Regulation Of JNK Cascade
MRNA Metabolic Process
Negative Regulation Of Stress-activated MAPK Cascade
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
SnRNA Import Into Nucleus
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Mitochondrial Fusion
Protein Localization To Mitochondrion
Establishment Of Protein Localization To Organelle
Nucleobase-containing Compound Metabolic Process
Cellular Localization
RNA Import Into Nucleus
Positive Regulation Of Protein Linear Polyubiquitination
Proepicardium Development
Regulation Of Cytokine-mediated Signaling Pathway
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Protein Targeting
Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Cellular Response To Dopamine
Dopamine Uptake Involved In Synaptic Transmission
Establishment Of Centrosome Localization
Adult Locomotory Behavior
Catabolic Process
Neuromuscular Process
Cellular Component Assembly
Protein Localization
Cellular Metabolic Process
Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Apoptotic Chromosome Condensation
Protein K29-linked Ubiquitination
Negative Regulation Of Mitochondrial Fusion
Cellular Response To Manganese Ion
Protein K27-linked Ubiquitination
Platelet Activating Factor Metabolic Process
Nuclear-transcribed MRNA Catabolic Process
Establishment Of Localization In Cell
Single Organism Reproductive Process
Regulation Of Mitochondrial Fusion
Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of MAPK Cascade
MRNA Catabolic Process
Regulation Of JNK Cascade
Adult Behavior
Positive Regulation Of Monocyte Differentiation
Tagcloud
?
1b1
1b3
abpp
acetylhydrolases
adapted
compound
confirm
determining
discovered
fluopol
hydrolases
ic50
impairs
library
nih
noncatalytic
p11
perturb
polarization
probes
profiling
reversible
screen
spermatogenesis
supporting
tetrahydropyridine
Tagcloud (Difference)
?
1b1
1b3
abpp
acetylhydrolases
adapted
compound
confirm
determining
discovered
fluopol
hydrolases
ic50
impairs
library
nih
noncatalytic
p11
perturb
polarization
probes
profiling
reversible
screen
spermatogenesis
supporting
tetrahydropyridine
Tagcloud (Intersection)
?