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KRT1 and FANCC
Number of citations of the paper that reports this interaction (PubMedID
14499622
)
0
Data Source:
BioGRID
(two hybrid)
KRT1
FANCC
Description
keratin 1
FA complementation group C
Image
GO Annotations
Cellular Component
Cornified Envelope
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Intermediate Filament
Plasma Membrane
Membrane
Keratin Filament
Extracellular Exosome
Blood Microparticle
Ficolin-1-rich Granule Lumen
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Fanconi Anaemia Nuclear Complex
Molecular Function
Protein Binding
Carbohydrate Binding
Structural Constituent Of Skin Epidermis
Signaling Receptor Activity
Protein Heterodimerization Activity
Protein Binding
Biological Process
Complement Activation, Lectin Pathway
Response To Oxidative Stress
Peptide Cross-linking
Keratinization
Fibrinolysis
Intermediate Filament Organization
Regulation Of Angiogenesis
Negative Regulation Of Inflammatory Response
Protein Heterotetramerization
Establishment Of Skin Barrier
DNA Repair
Nucleotide-excision Repair
DNA Damage Response
Cellular Response To Oxidative Stress
Interstrand Cross-link Repair
Protein-containing Complex Assembly
Pathways
Neutrophil degranulation
Keratinization
Formation of the cornified envelope
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Fanconi Anemia Pathway
TP53 Regulates Transcription of DNA Repair Genes
PKR-mediated signaling
Drugs
Zinc
Copper
Zinc acetate
Diseases
Ichthyosis hystrix, Curth-Macklin type
Epidermolytic palmoplantar keratoderma (EPPK)
Striate palmoplantar keratoderma
Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE)
Fanconi anemia
GWAS
Birth weight (
31043758
)
Hematocrit (
32888494
)
Offspring birth weight (
31043758
)
Polycystic ovary syndrome (
26284813
)
Interacting Genes
54 interacting genes:
-
AMOTL2
CALB2
CSTA
DSP
EVPL
F12
FANCA
FANCC
FFAR2
GOLGA2
GOLGA6L9
HAUS1
HMG20A
HOOK2
IVL
KNG1
KRT13
KRT14
KRT15
KRT16
KRT19
KRT24
KRT25
KRT26
KRT27
KRT28
KRT31
KRT33B
KRT34
KRT35
KRT36
KRT37
KRT38
KRT39
KRT40
KRT5
LINC00839
LORICRIN
MBL2
NINL
NUP62
OGT
PI3
PRKCE
RINT1
RNF26
SGTB
TFIP11
TLCD4
TRIM54
U2AF1
UBE3A
YWHAQ
54 interacting genes:
APC
AZIN1
BMPR1A
BUB1
CAPN10
CCNA2
CCND1
CDK1
CTBP1
DLC1
DNAJB1
EGFR
FANCA
FANCD2
FANCE
FANCF
FANCG
FBXW7
GSTP1
HSP90AA1
HSP90B1
HSPA1A
HSPA4
HSPA8
IK
KRAS
KRT1
MEOX2
MLH3
MT-ATP6
MUTYH
NRAS
PDGFRL
PIK3CA
PMS2
POR
PRDX3
PRPF31
PTPN12
PTPRJ
RB1
RPL18
RPS3A
SMAD4
SPTA1
SPTAN1
SRC
STAT1
STMN1
STMN2
TCERG1
TGFBR2
USP14
ZBTB32
Entrez ID
3848
2176
HPRD ID
00763
01967
Ensembl ID
ENSG00000167768
ENSG00000158169
Uniprot IDs
P04264
A0A024R9N2
A0A087WW44
B4E3W2
Q00597
PDB IDs
4ZRY
6E2J
6UUI
7KZP
7KZQ
7KZR
7KZS
7KZT
7KZV
Enriched GO Terms of Interacting Partners
?
Structural Constituent Of Skin Epidermis
Intermediate Filament Organization
Intermediate Filament-based Process
Intermediate Filament Cytoskeleton Organization
Keratin Filament
Intermediate Filament
Structural Molecule Activity
Epithelial Cell Differentiation
Cytoskeleton Organization
Supramolecular Fiber Organization
Morphogenesis Of An Epithelium
Tissue Morphogenesis
Cytoskeleton
Organelle Organization
Cornified Envelope
Peptide Cross-linking
Structural Constituent Of Cytoskeleton
Anatomical Structure Morphogenesis
Cell Differentiation
Keratinocyte Differentiation
Extracellular Exosome
Cellular Developmental Process
Epidermis Development
Cytosol
Epidermal Cell Differentiation
Keratinization
Hair Cycle
Developmental Process
Centrosome Cycle
Intermediate Filament Cytoskeleton
Hair Follicle Morphogenesis
Microtubule Organizing Center Organization
Protein Localization To Perinuclear Region Of Cytoplasm
Tissue Development
Cell Surface Pattern Recognition Receptor Signaling Pathway
Fanconi Anaemia Nuclear Complex
Cytosol
Regulation Of Programmed Cell Death
Regulation Of Cell Population Proliferation
Regulation Of Apoptotic Process
Negative Regulation Of Supramolecular Fiber Organization
Cellular Response To Stress
Response To Stress
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Cellular Component Organization
Negative Regulation Of Cytoskeleton Organization
Response To Hormone
Response To Growth Factor
Fanconi Anaemia Nuclear Complex
Cellular Response To Peptide Hormone Stimulus
ATP-dependent Protein Folding Chaperone
Cellular Response To Hormone Stimulus
Interstrand Cross-link Repair
Nucleoplasm
Regulation Of Supramolecular Fiber Organization
Response To Steroid Hormone
Regulation Of Organelle Organization
Negative Regulation Of Programmed Cell Death
Cadherin Binding
Positive Regulation Of Cell Population Proliferation
Nucleus
Focal Adhesion
Protein Folding Chaperone
Negative Regulation Of Apoptotic Process
Cellular Response To Oxygen-containing Compound
Regulation Of Multicellular Organismal Process
DNA Repair
Regulation Of Immune System Process
Negative Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Protein-containing Complex Disassembly
DNA Damage Response
Intracellular Signal Transduction
Response To Peptide Hormone
Regulation Of Cytoskeleton Organization
Response To Lipid
G1/S Transition Of Mitotic Cell Cycle
Nucleic Acid Metabolic Process
Macromolecule Metabolic Process
Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Cell Cycle Phase Transition
Cell Cycle G1/S Phase Transition
Response To Unfolded Protein
Regulation Of Cellular Component Organization
Regulation Of Cell Cycle Phase Transition
Regulation Of Protein Depolymerization
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Tagcloud (Difference)
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Tagcloud (Intersection)
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