KRT1 and IVL

Number of citations of the paper that reports this interaction (PMID 8999895)
22

Data Source:
BioGRID (pull down)

		KRT1	IVL
Gene Name		keratin 1, type II	involucrin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytoskeleton Plasma Membrane Membrane Extracellular Matrix Keratin Filament Extracellular Vesicular Exosome Blood Microparticle	Cornified Envelope Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Structural Molecule Activity Protein Binding Carbohydrate Binding	Structural Molecule Activity Protein Binding, Bridging
	Biological Process	Complement Activation, Lectin Pathway Retina Homeostasis Response To Oxidative Stress Fibrinolysis Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Establishment Of Skin Barrier	Response To UV-B Peptide Cross-linking Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Keratinocyte Differentiation Keratinization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: CALB2 CSTA DSP EVPL F12 FANCA FANCC IVL KNG1 KRT5 LOR MBL2 PI3 PRKCE YWHAQ	9 interactors: ACD CSTA DSP EVPL KRT1 LOR POT1 SPRR3 UCHL5
Entrez ID		3848	3713
HPRD ID		00763	00931
Ensembl ID		ENSG00000167768	ENSG00000163207
Uniprot IDs		P04264	P07476
PDB IDs			1EU0
Enriched GO Terms of Interacting Partners?		Peptide Cross-linking Keratinocyte Differentiation Epidermis Development Epidermal Cell Differentiation Skin Development Keratinization Epithelial Cell Differentiation Epithelium Development Blood Coagulation, Intrinsic Pathway Regulation Of Wound Healing Regulation Of Protein Processing Protein Activation Cascade Cytosolic Calcium Ion Homeostasis Tissue Development Positive Regulation Of Wound Healing Wound Healing Negative Regulation Of Endopeptidase Activity Negative Regulation Of Blood Coagulation Negative Regulation Of Peptidase Activity Negative Regulation Of Coagulation Positive Regulation Of Cellular Glucuronidation Response To Wounding Cellular Calcium Ion Homeostasis Negative Regulation Of Wound Healing Calcium Ion Homeostasis Positive Regulation Of Transport Anatomical Structure Development Acute Inflammatory Response Organ Development Negative Regulation Of Proteolysis Ventricular Compact Myocardium Morphogenesis Factor XII Activation TRAM-dependent Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity Regulation Of Blood Coagulation Negative Regulation Of Hydrolase Activity Cellular Metal Ion Homeostasis Regulation Of Peptidase Activity Blood Coagulation Inflammatory Response Developmental Process Hemostasis Protein Metabolic Process Cellular Cation Homeostasis Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Protein Localization To Adherens Junction Positive Regulation Of Fibrinolysis Cellular Ion Homeostasis Response To Stress	Peptide Cross-linking Skin Development Keratinocyte Differentiation Epidermal Cell Differentiation Epidermis Development Keratinization Epithelial Cell Differentiation Telomere Assembly Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomerase Activity Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase System Development Regulation Of Telomerase Activity Organ Development Multicellular Organismal Development Epithelium Development Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Anatomical Structure Development Developmental Process Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Tissue Development Positive Regulation Of DNA Replication Telomere Maintenance Cellular Protein Modification Process Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Ventricular Compact Myocardium Morphogenesis Protein Metabolic Process Regulation Of DNA Replication Telomere Formation Via Telomerase Positive Regulation Of DNA Metabolic Process Protein Localization To Adherens Junction Protection From Non-homologous End Joining At Telomere Cellular Protein Metabolic Process Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Helicase Activity Positive Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Catalytic Activity Regulation Of Chromosome Organization Complement Activation, Lectin Pathway Bundle Of His Cell To Purkinje Myocyte Communication Protein Localization To Cell Junction Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase
Tagcloud ?		arose backcrosses bareskin bsk chr clustered corneal den denuded facility granulin grn hair intersubspecific junctional jup keratin kinds linkage mapped opacity plakoglobin portion rara recombination resembling rex rim3 spontaneously	attack bleak chemotherapeutic cns deeply dehydrogenase detecting differs distinguish earnestly fdg imagery intravascular lactate lymphatic lymphoma lymphomatosis methotrexate pcnsl penetration permit powerful prognoses relapse rituximab sanctuary solely systemic ways
Tagcloud (Difference) ?		arose backcrosses bareskin bsk chr clustered corneal den denuded facility granulin grn hair intersubspecific junctional jup keratin kinds linkage mapped opacity plakoglobin portion rara recombination resembling rex rim3 spontaneously	attack bleak chemotherapeutic cns deeply dehydrogenase detecting differs distinguish earnestly fdg imagery intravascular lactate lymphatic lymphoma lymphomatosis methotrexate pcnsl penetration permit powerful prognoses relapse rituximab sanctuary solely systemic ways
Tagcloud (Intersection) ?