FHL2 and ADAM17

  • Number of citations of the paper that reports this interaction (PMID 16619241)
  • 5
  • Data Source:
  • HPRD (in vitro, two hybrid, in vivo)

FHL2

ADAM17

Gene Name four and a half LIM domains 2 ADAM metallopeptidase domain 17
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 92 interactors: ADAM17 AK1 APP AR ARHGAP9 ATXN1 BANP BLZF1 BMPR2 BRCA1 CAPN1 CARD8 CCDC92 CKM CREBBP CSK CSN2 CTNNB1 DCP1A DPF2 DTX2 DUSP10 E2F1 E2F2 E2F3 E2F4 EIF6 EP300 ESR1 FAM129A FAM154A FHL1 FHL3 FHL5 FOXO1 GLYR1 GNG12 HAND1 HIF1A ID3 IGFBP5 IKZF4 INCA1 ITGA3 ITGA7 ITGB1 ITGB2 ITGB5 ITGB6 JUP KANK2 KIAA1217 MCM7 MYBPC1 NRF1 PFKM PHB2 PSEN2 PUF60 RAI2 REL REV1 RFX3 RUNX2 SAP30BP SFPQ SIGLEC6 SLC34A1 SMAD2 SMAD3 SMAD4 SP2 SRF STAT3 TNFRSF11A TRAF6 TRIM55 TRIM63 TTN WT1 ZBTB16 ZFP64 ZFYVE9 ZMYM4 ZNF131 ZNF212 ZNF3 ZNF331 ZNF408 ZNF417 ZNF626 ZNF638 14 interactors: DLG1 ERBB4 FHL2 MAD2L1 MAD2L2 NOTCH1 PTPN3 SH3D19 TGFA TIMP3 TNF TNFRSF1A TNFRSF1B TNFSF11
Entrez ID 2274 6868
HPRD ID 04026 04703
Ensembl ID ENSG00000115641 ENSG00000151694
Uniprot IDs J3KNW4 Q14192 Q2XQU9 Q6I9R8 B2RNB2 P78536
PDB IDs 1X4K 1X4L 2D8Z 1BKC 1ZXC 2A8H 2DDF 2FV5 2FV9 2I47 2M2F 2OI0 3B92 3CKI 3E8R 3EDZ 3EWJ 3G42 3KMC 3KME 3L0T 3L0V 3LE9 3LEA 3LGP 3O64
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acted  adapter  converts  cytoplasm  cytoskeleton  deprived  deregulated  direction  e2  ehd2  enrichment  homer3  hydroxytamoxifen  mcf  modulator  oestrogen  oht  organelle  overlap  pf  rationale  remarkable  remodelling  reorganisation  reprogrammed  rhof  transcriptome  uncovered  unexpectedly 
anchored  apma  arguing  betacellulin  bzatp  cd23  cd62  chimeras  constitutive  convertase  cytoplasmic  disintegrin  dispensable  domain  ectodomain  influences  influx  ionomycin  metalloprotease  metalloproteinase  motif  negatively  pro  retention  shedding  tgfalpha  translationally  transmembrane 
Tagcloud (Difference) ?
acted  adapter  converts  cytoplasm  cytoskeleton  deprived  deregulated  direction  e2  ehd2  enrichment  homer3  hydroxytamoxifen  mcf  modulator  oestrogen  oht  organelle  overlap  pf  rationale  remarkable  remodelling  reorganisation  reprogrammed  rhof  transcriptome  uncovered  unexpectedly 
anchored  apma  arguing  betacellulin  bzatp  cd23  cd62  chimeras  constitutive  convertase  cytoplasmic  disintegrin  dispensable  domain  ectodomain  influences  influx  ionomycin  metalloprotease  metalloproteinase  motif  negatively  pro  retention  shedding  tgfalpha  translationally  transmembrane 
Tagcloud (Intersection) ?