FHL2 and DPF2

Number of citations of the paper that reports this interaction (PMID 18255255)
1

Data Source:
BioGRID (two hybrid, two hybrid)

		FHL2	DPF2
Gene Name		four and a half LIM domains 2	D4, zinc and double PHD fingers family 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Focal Adhesion Actin Cytoskeleton Z Disc M Band	Nuclear Chromatin Nucleoplasm Cytoplasm Centrosome Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Coactivator Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Identical Protein Binding Androgen Receptor Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Transcription, DNA-templated Response To Hormone Androgen Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated Atrial Cardiac Muscle Cell Development Ventricular Cardiac Muscle Cell Development Heart Trabecula Formation	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Apoptotic Process Apoptotic Signaling Pathway
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		92 interactors: ADAM17 AK1 APP AR ARHGAP9 ATXN1 BANP BLZF1 BMPR2 BRCA1 CAPN1 CARD8 CCDC92 CKM CREBBP CSK CSN2 CTNNB1 DCP1A DPF2 DTX2 DUSP10 E2F1 E2F2 E2F3 E2F4 EIF6 EP300 ESR1 FAM129A FAM154A FHL1 FHL3 FHL5 FOXO1 GLYR1 GNG12 HAND1 HIF1A ID3 IGFBP5 IKZF4 INCA1 ITGA3 ITGA7 ITGB1 ITGB2 ITGB5 ITGB6 JUP KANK2 KIAA1217 MCM7 MYBPC1 NRF1 PFKM PHB2 PSEN2 PUF60 RAI2 REL REV1 RFX3 RUNX2 SAP30BP SFPQ SIGLEC6 SLC34A1 SMAD2 SMAD3 SMAD4 SP2 SRF STAT3 TNFRSF11A TRAF6 TRIM55 TRIM63 TTN WT1 ZBTB16 ZFP64 ZFYVE9 ZMYM4 ZNF131 ZNF212 ZNF3 ZNF331 ZNF408 ZNF417 ZNF626 ZNF638	14 interactors: ESRRA ESRRB ESRRG FHL2 HIST1H3A HIST3H3 LDOC1 LNX1 NFKB2 REL RELB SMARCB1 UPF2 ZNF212
Entrez ID		2274	5977
HPRD ID		04026	03394
Ensembl ID		ENSG00000115641	ENSG00000133884
Uniprot IDs		J3KNW4 Q14192 Q2XQU9 Q6I9R8	B4DT58 J3KMZ8 Q92785
PDB IDs		1X4K 1X4L 2D8Z	3IUF
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression RNA Metabolic Process Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Transcription From RNA Polymerase II Promoter Organ Development Positive Regulation Of Transcription, DNA-templated Biosynthetic Process Embryo Development Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Developmental Process Negative Regulation Of Transcription, DNA-templated Formation Of Primary Germ Layer Negative Regulation Of Cellular Metabolic Process Tissue Development Anatomical Structure Morphogenesis Negative Regulation Of Nucleic Acid-templated Transcription Cellular Response To Organic Substance Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Gastrulation Regulation Of Signaling Anatomical Structure Development Response To Organic Substance Organ Morphogenesis Embryonic Morphogenesis	Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process NIK/NF-kappaB Signaling Intracellular Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Hormone-mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Metabolic Process Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Metabolic Process Response To Organic Substance DNA-templated Transcription, Initiation Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Follicular Dendritic Cell Differentiation Trophectodermal Cell Proliferation Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Blastocyst Development
Tagcloud ?		acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 ehd2 enrichment homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome uncovered unexpectedly	1alpha acetylated androgen associating baf45d biogenesis coactivator coactivators converted derepressed enhances err erralpha fingers hdac1 hela myoblast peroxisome pgc phd proliferator purification recognizing repressive repressor stably steroid superfamily transactivation
Tagcloud (Difference) ?		acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 ehd2 enrichment homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome uncovered unexpectedly	1alpha acetylated androgen associating baf45d biogenesis coactivator coactivators converted derepressed enhances err erralpha fingers hdac1 hela myoblast peroxisome pgc phd proliferator purification recognizing repressive repressor stably steroid superfamily transactivation
Tagcloud (Intersection) ?