FHL2 and YPEL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FHL2	YPEL3
Description		four and a half LIM domains 2	yippee like 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Focal Adhesion Z Disc	Nucleus Nucleolus
	Molecular Function	Transcription Corepressor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Identical Protein Binding BHLH Transcription Factor Binding Metal Ion Binding	Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Regulation Of Transcription By RNA Polymerase II Response To Hormone Negative Regulation Of Apoptotic Process Atrial Cardiac Muscle Cell Development Ventricular Cardiac Muscle Cell Development Heart Trabecula Formation Negative Regulation Of Calcineurin-NFAT Signaling Cascade	Positive Regulation Of Cellular Senescence
Pathways		PPARA activates gene expression
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Bipolar disorder x sex interaction ( 34099189) Body fat mass ( 28552196) Hip circumference adjusted for BMI ( 34021172) Household income (MTAG) ( 31844048) Lung cancer in ever smokers ( 28604730) PR interval ( 32439900) Pulse pressure ( 30224653 30578418) Walking pace ( 33128006)	Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Schizophrenia ( 25056061 28991256 29483656)
Interacting Genes		175 interacting genes: A1CF ABI1 ABLIM1 ADAM17 AK1 AKIP1 AMOT ANKRD55 APP AR ARHGAP9 ATOSB ATXN1 BANP BARX2 BIN1 BLZF1 BMPR2 BRCA1 CACNA1C CAND2 CAPN1 CARD8 CATSPERT CCDC198 CCDC92 CDC73 CFTR CIMIP1 CKM CREBBP CSK CSN2 CTNNB1 DAPL1 DCP1A DDIT4L DLGAP1 DPF2 DRC4 DTX2 DUSP10 E2F1 E2F2 E2F3 E2F4 EP300 ESR1 FAM204A FHL1 FHL3 FHL5 FOXO1 GATAD2B GLYR1 GMEB2 GNG12 GNG4 GOLGA6A GTF2F2 GTF2H1 HAND1 HCK HSF2BP HSPB2 ID3 IDH1 IER3 IFI35 IGFBP5 IKZF1 IKZF4 IL16 INCA1 ITGA3 ITGA7 ITGB1 ITGB2 ITGB5 ITGB6 JUP KANK2 KIAA1217 KIF5B KLF12 KLHL20 KPRP LDLRAP1 LRIF1 MAGEL2 MBD3L1 MCM7 MDM2 MISP MYBPC1 MYO15B NBPF6 NIBAN1 NRF1 PFKM PHB2 PHF1 PHF21A PKNOX1 PKNOX2 POGZ POU6F2 PRDM11 PRDM6 PRR5L PSEN2 PUF60 QRICH1 RAI2 REL REV1 RFX3 RIPPLY1 RUNX2 SAP30BP SAXO1 SAXO2 SAXO4 SCNM1 SFPQ SH3RF1 SIGLEC6 SLAIN1 SLC34A1 SMAD2 SMAD3 SMAD4 SNAI1 SOX30 SP2 SPRY4 SREBF2 SRF STAT3 SUMO1P1 TCP10L TNFRSF11A TOX3 TRAF6 TRIM55 TRIM63 TRIM73 TTN TXNRD3 VXN WASHC1 WT1 YPEL3 YY1 ZBTB16 ZBTB25 ZFP64 ZFYVE9 ZMYM4 ZNF131 ZNF143 ZNF200 ZNF212 ZNF23 ZNF3 ZNF331 ZNF408 ZNF410 ZNF417 ZNF620 ZNF626 ZNF638 ZNF655 ZNF85 ZSCAN9	122 interacting genes: ACTMAP AIRIM APP ARMC7 ATG9A ATXN1L BCAS2 C10orf55 CABP2 CDCA4 CDKN2D COL8A1 CRYBA1 CRYBA2 CYB5R2 CYSRT1 DMRT3 DOK6 DOK7 EID2B FAM168B FANCL FGF21 FHL2 FHL3 FHL5 FNDC3B FRS3 GCA GCM2 GEM GUCD1 HDAC7 HEXIM2 HGS HNRNPH1 HOXA1 HR HSD3B7 HSPB2 HSPB2-C11orf52 INTS11 KLHL38 KRTAP13-2 KRTAP15-1 KRTAP23-1 KRTAP3-1 KRTAP3-3 KRTAP6-2 LARP4 LIMS3 LIMS4 LMO2 LONRF1 MAD2L2 MDFI MKRN3 MORN3 MYOZ1 MYOZ3 NRF1 NUFIP2 ODAM OSTF1 OTX1 PIK3R3 PITX1 PLSCR4 POLD1 POLR1C POU2AF1 PPP2CA PRKAA2 PRKAB2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 QRICH1 RBPMS RFC5 SH2D4A SHC3 SMUG1 SPAG8 SPG21 SPRYD7 SRPK2 STK16 TASOR2 TBX6 TENT5A TENT5B TEPSIN TGM7 TLE5 TLX3 TOX2 TP53INP1 TRAPPC2L TRAPPC6A TRIM10 TRIM55 TRIM63 TRIM73 TRIP6 TSC1 TSSK3 UBASH3A UBTD2 VENTX VGLL3 VWC2L WWOX ZIC1 ZNF441 ZNF76 ZNF765 ZYX
Entrez ID		2274	83719
HPRD ID		04026	15683
Ensembl ID		ENSG00000115641	ENSG00000090238
Uniprot IDs		Q14192 Q2XQU9 Q6I9R8	P61236
PDB IDs		1X4K 1X4L 2D8Z 2MIU
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding Negative Regulation Of DNA-templated Transcription Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Metabolic Process Sequence-specific DNA Binding Zinc Ion Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Positive Regulation Of Metabolic Process Transcription Regulator Complex Metal Ion Binding Regulation Of MiRNA Transcription Sequence-specific Double-stranded DNA Binding Chromatin Regulation Of MiRNA Metabolic Process Nucleoplasm DNA-templated Transcription Formation Of Primary Germ Layer Integrin Complex Transcription By RNA Polymerase II RNA Polymerase II Transcription Regulator Complex	Protein Binding Nucleus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?