TRPV5 and CALB1

Number of citations of the paper that reports this interaction (PubMedID 16763551)
48

Data Source:
HPRD (in vitro, in vivo)

		TRPV5	CALB1
Description		transient receptor potential cation channel subfamily V member 5	calbindin 1
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GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane Calcium Channel Complex	Nucleus Cytoplasm Cytosol Axon Dendrite Stereocilium Cuticular Plate Neuron Projection Neuronal Cell Body Terminal Bouton Calyx Of Held Synapse Extracellular Exosome Hippocampal Mossy Fiber To CA3 Synapse Postsynapse Glutamatergic Synapse GABA-ergic Synapse Presynaptic Cytosol Postsynaptic Cytosol
	Molecular Function	Monoatomic Ion Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding Metal Ion Binding	Vitamin D Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Metal Ion Binding Calcium Ion Binding Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Calcium Ion Binding Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Urine Volume Protein Homotetramerization Calcium Ion Homeostasis Transmembrane Transport Calcium Ion Transport Into Cytosol Calcium Ion Transmembrane Transport Calcium Ion Import Across Plasma Membrane	Learning Or Memory Short-term Memory Long-term Memory Locomotory Behavior Retina Layer Formation Response To Auditory Stimulus Metanephric Part Of Ureteric Bud Development Regulation Of Synaptic Plasticity Calcium Ion Homeostasis Retina Development In Camera-type Eye Metanephric Collecting Duct Development Metanephric Distal Convoluted Tubule Development Metanephric Connecting Tubule Development Cochlea Development Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration
Pathways		TRP channels	Amyloid fiber formation
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Cancer ( 29299148) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)	Chronotype ( 27494321 30696823) Morning vs. evening chronotype ( 27494321)
Interacting Genes		4 interacting genes: ANXA2 CALB1 EWSR1 S100A10	6 interacting genes: CACNA1D IKBKG IMPA1 RANBP9 TRPV5 TRPV6
Entrez ID		56302	793
HPRD ID		05981	00229
Ensembl ID		ENSG00000127412	ENSG00000104327
Uniprot IDs		Q9NQA5	P05937
PDB IDs		5OEO	6FIE
Enriched GO Terms of Interacting Partners?		AnxA2-p11 Complex Positive Regulation Of Plasma Membrane Repair Regulation Of Plasma Membrane Repair Positive Regulation Of Plasminogen Activation Membrane Raft Assembly Regulation Of Plasma Membrane Organization Plasma Membrane Protein Complex Regulation Of Plasminogen Activation Positive Regulation Of Protein Processing Positive Regulation Of Protein Maturation Membrane Raft Organization Vesicle Budding From Membrane MRNA Transcription By RNA Polymerase II Membrane Assembly Regulation Of Protein Processing MRNA Transcription Regulation Of Protein Maturation Calcium-dependent Protein Binding Positive Regulation Of Exocytosis Calcium Ion Binding Metanephric Connecting Tubule Development Calcium Ion Binding Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Nuclear Matrix RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport PCSK9-AnxA2 Complex Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Calcium Ion Binding Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Exocytosis Negative Regulation Of Receptor Catabolic Process Positive Regulation Of Intracellular Cholesterol Transport Positive Regulation Of Proteolysis Membrane Raft Positive Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Intracellular Lipid Transport Metanephric Part Of Ureteric Bud Development Metanephric Distal Convoluted Tubule Development Myelin Sheath Adaxonal Region Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Vitamin D Binding Osteoclast Development Phospholipase A2 Inhibitor Activity Transcription By RNA Polymerase II Positive Regulation Of Secretion By Cell Regulation Of Intracellular Cholesterol Transport Cuticular Plate Vesicle Organization Positive Regulation Of Secretion Regulation Of Intracellular Lipid Transport Phospholipase Inhibitor Activity	Calcium Ion Import Across Plasma Membrane Calcium Ion Import Into Cytosol Calcium Ion Import Calcium Ion Transmembrane Import Into Cytosol Calcium Channel Activity Inorganic Cation Import Across Plasma Membrane Import Across Plasma Membrane Monoatomic Ion Channel Activity Calcium Ion Transmembrane Transport Calcium Channel Complex Calcium Ion Transport Voltage-gated Calcium Channel Activity Involved SA Node Cell Action Potential Glycerol-2-phosphatase Activity Lithium Ion Binding Inositol Monophosphate 4-phosphatase Activity Inositol Monophosphate Phosphatase Activity Inositol Monophosphate 1-phosphatase Activity Glucose-1-phosphatase Activity Inositol Monophosphate 3-phosphatase Activity Fructose-1-phosphatase Activity Ubiquitin Ligase Complex Parathyroid Hormone Secretion Metal Ion Transport Import Into Cell Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Voltage-gated Calcium Channel Activity Involved In Cardiac Muscle Cell Action Potential Inositol Biosynthetic Process Glucose-6-phosphatase Activity Linear Polyubiquitin Binding Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Membrane Depolarization During SA Node Cell Action Potential Calmodulin Binding Metal Ion Binding Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Inositol Metabolic Process IkappaB Kinase Complex Calcium Ion Homeostasis Monoatomic Ion Transport L-type Voltage-gated Calcium Channel Complex Transferrin Receptor Binding Anoikis High Voltage-gated Calcium Channel Activity Calcium Ion Transport Into Cytosol Transmembrane Transport Alpha-actinin Binding Membrane Depolarization During Cardiac Muscle Cell Action Potential Ankyrin Binding
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