TRPV5 and S100A10

Number of citations of the paper that reports this interaction (PubMedID 12660155)
44

Data Source:
BioGRID (pull down)

		TRPV5	S100A10
Description		transient receptor potential cation channel subfamily V member 5	S100 calcium binding protein A10
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane Calcium Channel Complex	Extracellular Region Cytoplasm Plasma Membrane Cell Surface Nuclear Matrix Extracellular Matrix Membrane Raft Extracellular Exosome RNA Polymerase II Transcription Regulator Complex Plasma Membrane Protein Complex AnxA2-p11 Complex
	Molecular Function	Monoatomic Ion Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Lipid Binding Protein Homodimerization Activity Transmembrane Transporter Binding Calcium-dependent Protein Binding
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Urine Volume Protein Homotetramerization Calcium Ion Homeostasis Transmembrane Transport Calcium Ion Transport Into Cytosol Calcium Ion Transmembrane Transport Calcium Ion Import Across Plasma Membrane	Membrane Raft Assembly Vesicle Budding From Membrane Positive Regulation Of Plasminogen Activation MRNA Transcription By RNA Polymerase II Positive Regulation Of GTPase Activity Positive Regulation Of Exocytosis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Neurogenesis Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Plasma Membrane Repair
Pathways		TRP channels	Dissolution of Fibrin Clot
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Cancer ( 29299148) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)	Asthma ( 31619474) Diverticular disease ( 30177863) Serum metabolite levels ( 33031748) Urinary metabolite levels in chronic kidney disease ( 29545352) Urinary metabolite ratios in chronic kidney disease ( 29545352)
Interacting Genes		4 interacting genes: ANXA2 CALB1 EWSR1 S100A10	23 interacting genes: ANXA2 ANXA7 BAD CBR3 CDK16 COPS6 CTSB DSCAM ERBB3 FSHR KCNK3 MLKL NANOS2 PLA2G4C PLG S100A3 S100Z SETDB1 SUMO2 TRPV5 TRPV6 USP2 ZGPAT
Entrez ID		56302	6281
HPRD ID		05981	00232
Ensembl ID		ENSG00000127412	ENSG00000197747
Uniprot IDs		Q9NQA5	P60903
PDB IDs		5OEO	1A4P 1BT6 4DRW 4FTG 4HRE 4HRG 4HRH
Enriched GO Terms of Interacting Partners?		AnxA2-p11 Complex Positive Regulation Of Plasma Membrane Repair Regulation Of Plasma Membrane Repair Positive Regulation Of Plasminogen Activation Membrane Raft Assembly Regulation Of Plasma Membrane Organization Plasma Membrane Protein Complex Regulation Of Plasminogen Activation Positive Regulation Of Protein Processing Positive Regulation Of Protein Maturation Membrane Raft Organization Vesicle Budding From Membrane MRNA Transcription By RNA Polymerase II Membrane Assembly Regulation Of Protein Processing MRNA Transcription Regulation Of Protein Maturation Calcium-dependent Protein Binding Positive Regulation Of Exocytosis Calcium Ion Binding Metanephric Connecting Tubule Development Calcium Ion Binding Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Nuclear Matrix RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport PCSK9-AnxA2 Complex Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Calcium Ion Binding Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Exocytosis Negative Regulation Of Receptor Catabolic Process Positive Regulation Of Intracellular Cholesterol Transport Positive Regulation Of Proteolysis Membrane Raft Positive Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Intracellular Lipid Transport Metanephric Part Of Ureteric Bud Development Metanephric Distal Convoluted Tubule Development Myelin Sheath Adaxonal Region Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Vitamin D Binding Osteoclast Development Phospholipase A2 Inhibitor Activity Transcription By RNA Polymerase II Positive Regulation Of Secretion By Cell Regulation Of Intracellular Cholesterol Transport Cuticular Plate Vesicle Organization Positive Regulation Of Secretion Regulation Of Intracellular Lipid Transport Phospholipase Inhibitor Activity	Calcium-dependent Protein Binding Calcium-dependent Phospholipid Binding Plasma Membrane S100 Protein Binding
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