GULP1 and SMC2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GULP1	SMC2
Gene Name		GULP, engulfment adaptor PTB domain containing 1	structural maintenance of chromosomes 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nuclear Chromosome Condensed Chromosome Condensin Complex Nucleus Nucleoplasm Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Signal Transducer Activity	Protein Binding ATP Binding Protein Heterodimerization Activity
	Biological Process	Lipid Transport Phagocytosis, Engulfment Apoptotic Process Signal Transduction	Mitotic Cell Cycle Mitotic Chromosome Condensation Meiotic Chromosome Condensation Meiotic Chromosome Segregation Cell Division Kinetochore Organization
Pathways			Mitotic Prometaphase Mitotic Prophase Condensation of Prophase Chromosomes Cell Cycle, Mitotic M Phase Condensation of Prometaphase Chromosomes
Drugs
Diseases
GWAS			Orofacial clefts (interaction) ( 21618603)
Protein-Protein Interactions		4 interactors: CREB3L2 EPS8 LRP1 SMC2	8 interactors: ABCC5 DISC1 DNMT3B GULP1 LIG4 NCAPD2 SMC4 TRAF3IP1
Entrez ID		51454	10592
HPRD ID		12181	09277
Ensembl ID			ENSG00000136824
Uniprot IDs		Q9UBP9	A8K984 B3KMB1 B7ZLZ7 O95347 Q05BV1 Q05D74 Q6IPS5 Q7Z2X1
PDB IDs
Enriched GO Terms of Interacting Partners?		Beta-amyloid Clearance Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Actin Polymerization-dependent Cell Motility Mitotic Nuclear Division Exit From Mitosis Regulation Of Actin Cytoskeleton Organization Behavioral Response To Ethanol Meiotic Chromosome Condensation Regulation Of Actin Filament-based Process Regulation Of Phospholipase A2 Activity Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Cytoskeleton Organization Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Rac Protein Signal Transduction Negative Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Cholesterol Efflux Lipoprotein Transport Positive Regulation Of Cholesterol Transport Barbed-end Actin Filament Capping Actin Crosslink Formation Dendritic Cell Migration Regulation Of Cholesterol Efflux Aorta Morphogenesis Mitotic Chromosome Condensation Mitotic Cell Cycle Process Aorta Development Kinetochore Organization Cell Proliferation Apoptotic Cell Clearance Mitotic Cell Cycle Regulation Of Cholesterol Transport Regulation Of Smooth Muscle Cell Migration	Mitotic Chromosome Condensation Chromosome Condensation Organelle Organization Chromosome Organization DNA Metabolic Process Positive Regulation Of Neurogenesis Mitotic Sister Chromatid Segregation Cell Division DNA Ligation Involved In DNA Recombination Sister Chromatid Segregation Positive Regulation Of Cell Development S-adenosylmethioninamine Metabolic Process Response To Ionizing Radiation Regulation Of Neurogenesis Meiotic Chromosome Condensation DNA Methylation On Cytosine Within A CG Sequence DNA Packaging C-5 Methylation Of Cytosine Lagging Strand Elongation Pro-B Cell Differentiation S-adenosylhomocysteine Metabolic Process Regulation Of Cell Development Positive Regulation Of Cell Differentiation Chromosome Segregation Methylation-dependent Chromatin Silencing Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Establishment Of Integrated Proviral Latency Immunoglobulin V(D)J Recombination Establishment Of Viral Latency T Cell Receptor V(D)J Recombination Hyaluronan Biosynthetic Process DNA Ligation Involved In DNA Repair DNA Conformation Change Lymphoid Progenitor Cell Differentiation Negative Regulation Of Histone H3-K9 Methylation DNA Methylation On Cytosine Nervous System Development Phagocytosis, Engulfment Mitotic Nuclear Division Negative Regulation Of Interferon-beta Production DNA Ligation Positive Regulation Of Histone H3-K4 Methylation Nucleotide-excision Repair, DNA Gap Filling Mitochondrial Calcium Ion Homeostasis Cellular Response To Lithium Ion Membrane Invagination Protein Complex Localization Negative Regulation Of Histone Methylation Regulation Of Synapse Maturation Post-anal Tail Morphogenesis
Tagcloud ?		adaptor adaptors additionally another app binds characterize differential engulfment fe65 functionally influencing intracellular lipoprotein lrp1 mediate mediates motifs npxy phosphotyrosine plasmid precursor ptb reporter signalling supported thereby trafficking transactivation	called complementary cyclins dissociated dnas ectopic elucidate eventually g2 gst hec heptad hydrolyzes inhibits interacts leucine mitosis mitotic modulate mss1 nek2 p45 proteasome proteolysis pull repeats seventh smc1 telophase
Tagcloud (Difference) ?		adaptor adaptors additionally another app binds characterize differential engulfment fe65 functionally influencing intracellular lipoprotein lrp1 mediate mediates motifs npxy phosphotyrosine plasmid precursor ptb reporter signalling supported thereby trafficking transactivation	called complementary cyclins dissociated dnas ectopic elucidate eventually g2 gst hec heptad hydrolyzes inhibits interacts leucine mitosis mitotic modulate mss1 nek2 p45 proteasome proteolysis pull repeats seventh smc1 telophase
Tagcloud (Intersection) ?