RRAS and MRPL36

Number of citations of the paper that reports this interaction (PubMedID 18624398)
0

Data Source:
BioGRID (two hybrid)

		RRAS	MRPL36
Description		RAS related	mitochondrial ribosomal protein L36
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GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Membrane Extracellular Exosome	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Ribosome Nuclear Body Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Protein-containing Complex Binding	Structural Constituent Of Ribosome Protein Binding
	Biological Process	Leukocyte Differentiation Signal Transduction Ras Protein Signal Transduction Positive Regulation Of Endothelial Cell Migration Cell Migration Schwann Cell Migration Positive Regulation Of Angiogenesis Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Face Morphogenesis Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Schwann Cell Migration Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Positive Regulation Of Vasculogenesis	Translation Mitochondrial Translation
Pathways		SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) Pulse pressure ( 27618447) Schizophrenia ( 25056061 29483656) Systolic blood pressure ( 27618447)	Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627)
Interacting Genes		17 interacting genes: ACY3 AFDN ARAF BCL2 EEF1A1 EPHB2 MRPL36 NAV2 NCK1 PPP2CA RAF1 RALGDS RASIP1 RASSF5 SOS1 TRIM55 TRIM63	2 interacting genes: CIDEB RRAS
Entrez ID		6237	64979
HPRD ID		01299	14756
Ensembl ID		ENSG00000126458	ENSG00000171421
Uniprot IDs		P10301	Q9P0J6
PDB IDs		2FN4 7S0Z	3J7Y 3J9M 5OOL 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OIC 7OID 7OIE 7PD3 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8QSJ 8RRI 8XT0 8XT1 8XT2 8XT3
Enriched GO Terms of Interacting Partners?		Regulation Of Mononuclear Cell Proliferation Regulation Of Leukocyte Proliferation Signal Transduction Lymphocyte Homeostasis Regulation Of Intracellular Signal Transduction Leukocyte Homeostasis Lymphocyte Activation Pore Complex Regulation Of Phosphorus Metabolic Process Regulation Of Lymphocyte Activation Leukocyte Activation Immune System Process Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Glycolytic Process Schwann Cell Development Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation MAP Kinase Kinase Kinase Activity Negative Regulation Of ATP Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cell Activation B Cell Homeostasis Cell Activation Neurotrophin Signaling Pathway Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Lymphocyte Proliferation Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Catabolic Process Insulin-like Growth Factor Receptor Signaling Pathway Protein Modification Process Cytoplasm T Cell Homeostasis Positive Regulation Of Leukocyte Proliferation Negative Regulation Of Phosphate Metabolic Process Negative Regulation Of Intracellular Signal Transduction Regulation Of Protein-containing Complex Assembly Intracellular Signal Transduction Protein Metabolic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Cellular PH Reduction Positive Regulation Of B Cell Proliferation Homeostasis Of Number Of Cells Ribosome Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cell-cell Junction Positive Regulation Of Protein-containing Complex Assembly RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity	Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Protein-containing Complex Binding Schwann Cell Migration Negative Regulation Of Glial Cell Migration Negative Regulation Of Schwann Cell Migration Hyaloid Vascular Plexus Regression Norepinephrine Uptake Dopamine Uptake Involved In Synaptic Transmission Catecholamine Catabolic Process Amine Binding Heterocyclic Compound Binding Monoamine Transmembrane Transporter Activity Norepinephrine:sodium Symporter Activity Dopamine Binding Norepinephrine Transport Dopamine Biosynthetic Process Dopamine:sodium Symporter Activity Adenohypophysis Development Dopamine Catabolic Process Flotillin Complex Lipid Droplet Fusion Catecholamine Uptake Dopamine Uptake Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Vasculogenesis Dopaminergic Synapse Prepulse Inhibition Anatomical Structure Regression COPI-coated Vesicle Lipid Transfer Activity Regulation Of Vasculogenesis Neurotransmitter Transmembrane Transporter Activity COPII Vesicle Coat Regulation Of Dopamine Metabolic Process Dopamine Transport Neurotransmitter Reuptake Catecholamine Biosynthetic Process COPII-coated Vesicle Cargo Loading Regulation Of Glial Cell Migration Plasma Lipoprotein Particle Assembly Execution Phase Of Apoptosis Phosphatidic Acid Binding Protein-lipid Complex Assembly Glial Cell Migration Protein Phosphatase 2A Binding Monoamine Transport Neurotransmitter Uptake Face Morphogenesis Response To Iron Ion Positive Regulation Of Multicellular Organism Growth
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