CLEC7A and AIP

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CLEC7A	AIP
Gene Name		C-type lectin domain family 7, member A	aryl hydrocarbon receptor interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Membrane	Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Signaling Pattern Recognition Receptor Activity Carbohydrate Binding MHC Protein Binding Metal Ion Binding	Transcription Coactivator Activity Signal Transducer Activity Protein Binding Transcription Factor Binding GAF Domain Binding Unfolded Protein Binding
	Biological Process	Pattern Recognition Receptor Signaling Pathway Phagocytosis, Recognition Inflammatory Response Cell Recognition Carbohydrate Mediated Signaling T Cell Activation Defense Response To Protozoan Innate Immune Response	Protein Targeting To Mitochondrion Xenobiotic Metabolic Process Signal Transduction Regulation Of Protein Kinase A Signaling Protein Maturation By Protein Folding Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: ADAM33 AIP BNIP3 BNIP3L CALM3 FAM3A HSPD1 IL1RL1 JAGN1 KTN1 NINJ2 OCLN PTTG1IP RANBP9 SMIM3 SYNE4 TMEM79 TMPRSS4	16 interactors: AHR ARNT CLEC7A CSNK2A1 EGFR GNA13 GNAQ HSP90AA1 IKBKG IRF7 PDE4A PPARA PTGES3 STIP1 TNNI3K TOMM20
Entrez ID		64581	9049
HPRD ID		08396	10408
Ensembl ID		ENSG00000172243	ENSG00000110711
Uniprot IDs		Q68D78 Q9BXN2	O00170
PDB IDs			2LKN 4AIF 4APO
Enriched GO Terms of Interacting Partners?		Mitochondrial Protein Catabolic Process Mitochondrial Outer Membrane Permeabilization Positive Regulation Of Macrophage Activation Establishment Of Localization In Cell Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Mitochondrial Membrane Permeability Cellular Localization Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrion Organization Regulation Of Macrophage Activation Mitochondrial Transport Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Protein Maturation Programmed Cell Death Cell Death Death Transport B Cell Cytokine Production Interleukin-33-mediated Signaling Pathway Granulocyte Colony-stimulating Factor Signaling Pathway Isotype Switching To IgG Isotypes Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Mitochondrial Membrane Organization Apoptotic Mitochondrial Changes Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Regulation Of Interferon-gamma Production Exocytosis Establishment Of Protein Localization To Organelle Neutrophil Differentiation Cuticle Development Protein Transport Immune System Process Establishment Of Protein Localization Cornification Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Reactive Oxygen Species Metabolic Process Protein Targeting Intracellular Transport Protein Import Into Nucleus Establishment Of Epithelial Cell Apical/basal Polarity Negative Regulation Of Mitochondrial Fusion Granzyme-mediated Apoptotic Signaling Pathway Nuclear Import Apoptotic Process Autophagic Cell Death Regulation Of Mitochondrial Fusion Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of High Voltage-gated Calcium Channel Activity	Intracellular Receptor Signaling Pathway Signal Transduction Response To Stress Signaling Cell Communication Immune Response-regulating Signaling Pathway Regulation Of Immune System Process Positive Regulation Of Metabolic Process Cellular Response To Stimulus Positive Regulation Of Phospholipase Activity Response To Stimulus Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Rhythmic Process Protein Refolding Response To External Stimulus Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Catenin Import Into Nucleus Activation Of Innate Immune Response Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Glycolytic Process Regulation Of Cellular Response To Heat Circadian Rhythm Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Innate Immune Response Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Gene Expression Negative Regulation Of Cell Death Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Activation Of Phospholipase C Activity Response To Abiotic Stimulus Regulation Of Innate Immune Response Cellular Response To Drug Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Phospholipase C Activity Positive Regulation Of Immune Response Fc Receptor Signaling Pathway Alkanesulfonate Metabolic Process Regulation Of Glycolytic By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Nitric Oxide Biosynthetic Process Protein Transmembrane Transport Toll-like Receptor 9 Signaling Pathway
Tagcloud ?		amplifiable batch bioreactor chose cmv dectin destabilized dhfr flask functionality fungal glucans glycoproteins glycosylated ires lectin minimize mtx opinion pest pools prr sdectin shake stably titer titers walls zymosan	aminolaevulinate aspect autosomal coproporphyria counterparts cutanea decarboxylase dehydratase develops elucidating hepatoerythropoietic hereditary heteroallelic homo inherited intermittent mutational overt pct porphyria porphyrias puberty rarely recessive tarda uncommon uroporphyrinogen variegate vp
Tagcloud (Difference) ?		amplifiable batch bioreactor chose cmv dectin destabilized dhfr flask functionality fungal glucans glycoproteins glycosylated ires lectin minimize mtx opinion pest pools prr sdectin shake stably titer titers walls zymosan	aminolaevulinate aspect autosomal coproporphyria counterparts cutanea decarboxylase dehydratase develops elucidating hepatoerythropoietic hereditary heteroallelic homo inherited intermittent mutational overt pct porphyria porphyrias puberty rarely recessive tarda uncommon uroporphyrinogen variegate vp
Tagcloud (Intersection) ?