CSNK1E and KAT7

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		CSNK1E	KAT7
Gene Name		casein kinase 1, epsilon	K(lysine) acetyltransferase 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ribonucleoprotein Complex	Histone Acetyltransferase Complex Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Poly(A) RNA Binding	Sequence-specific DNA Binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Repair Protein Phosphorylation Endocytosis Organelle Organization Signal Transduction Circadian Rhythm Regulation Of Cell Shape Wnt Signaling Pathway Peptidyl-serine Phosphorylation Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Circadian Regulation Of Gene Expression Cellular Protein Localization Regulation Of Circadian Rhythm Positive Regulation Of Canonical Wnt Signaling Pathway	DNA Replication Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation
Pathways		Organelle biogenesis and maintenance misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling G2/M Transition Assembly of the primary cilium Signaling by Wnt Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic WNT mediated activation of DVL Loss of proteins required for interphase microtubule organizationÂ from the centrosome TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation Loss of Nlp from mitotic centrosomes XAV939 inhibits tankyrase, stabilizing AXIN Centrosome maturation Signaling by WNT in cancer Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: AKAP9 ANKRD6 APC APP ARHGEF1 ARNTL AXIN1 AXIN2 BBS10 BID C2orf44 CADM4 CRY1 DVL1 DVL2 DVL3 FAM110A FAM110C FAM83D FBP1 GTF3C1 HES1 KAT7 MCC NCOA3 PER1 PER2 PER3 PNO1 PPP1CA PPP1R14A RAD54B RBX1 SDCCAG3 SOCS3 TAOK1 TAZ TNS2 ZMYND8 ZNF227	43 interactors: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN HAP1 HIST1H3A HIST1H4A HIST2H2AC HOOK2 ING4 JADE1 KATNBL1 KCTD13 KIAA1377 LRIF1 MCM2 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPT5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165
Entrez ID		1454	11143
HPRD ID		02919	07135
Ensembl ID		ENSG00000213923	ENSG00000136504
Uniprot IDs		B0QY34 P49674 Q5U045	O95251
PDB IDs		4HNI 4HOK
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Signaling Regulation Of Wnt Signaling Pathway Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Wnt Signaling Pathway Regulation Of Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Circadian Regulation Of Gene Expression Regulation Of Phosphorus Metabolic Process Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Signal Transduction Signal Transduction Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Negative Regulation Of Glucocorticoid Receptor Signaling Pathway Cellular Response To Stimulus Regulation Of Intracellular Signal Transduction Wnt Signaling Pathway Signaling Regulation Of JNK Cascade Circadian Rhythm Cell Communication Canonical Wnt Signaling Pathway Regulation Of Stress-activated MAPK Cascade Planar Cell Polarity Pathway Involved In Neural Tube Closure Cochlea Development Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Positive Regulation Of JNK Cascade Regulation Of Protein Kinase Activity Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Positive Regulation Of Protein Metabolic Process Regulation Of Epithelial Cell Differentiation Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Kinase Activity Regulation Of Cell Differentiation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Stimulus Wnt Signaling Pathway, Planar Cell Polarity Pathway Epithelium Development Positive Regulation Of Metabolic Process Entrainment Of Circadian Clock By Photoperiod	Cell Cycle Cell Cycle Process Mitotic Cell Cycle DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Organelle Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Replication Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA-dependent DNA Replication Negative Regulation Of Biosynthetic Process Neuron Apoptotic Process Regulation Of RNA Metabolic Process Apoptotic Process Neuron Death Programmed Cell Death Regulation Of Transcription, DNA-templated Cell Death Death Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Replication Initiation Regulation Of Cell Cycle Establishment Of Vesicle Localization Vesicle Localization Negative Regulation Of Cellular Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Viral Process Chromosome Organization Regulation Of Cell Cycle Phase Transition Cellular Macromolecule Biosynthetic Process Cellular Process Macromolecule Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of DNA Replication Negative Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Microtubule-based Transport
Tagcloud ?		accessible applicable cancerous chosen constitute crc ctnnb1 hct ihc integrated isogenic kill leave lethality msh2 pairs polb ranked rb1 rko rnai sl synergistically therapeutics top tp53 uncovering verified wnt5a	acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently therapeutics throughput tnbc xenografts
Tagcloud (Difference) ?		accessible applicable cancerous chosen constitute crc ctnnb1 hct ihc integrated isogenic kill leave lethality msh2 pairs polb ranked rb1 rko rnai sl synergistically top tp53 uncovering verified wnt5a	acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently throughput tnbc xenografts
Tagcloud (Intersection) ?		therapeutics