KAT7 and ING4

Number of citations of the paper that reports this interaction (PMID 16387653)
126

Data Source:
HPRD (in vivo)

		KAT7	ING4
Gene Name		K(lysine) acetyltransferase 7	inhibitor of growth family, member 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Nucleolus Cytoplasm	Histone Acetyltransferase Complex Nucleus Nucleoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	DNA Replication Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation	DNA Replication Chromatin Organization Protein Acetylation Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Cell Cycle Arrest Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Growth
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN HAP1 HIST1H3A HIST1H4A HIST2H2AC HOOK2 ING4 JADE1 KATNBL1 KCTD13 KIAA1377 LRIF1 MCM2 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPT5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165	17 interactors: CDC34 EGLN1 EP300 HIST1H3A HIST3H3 HNRNPD HOXB9 JADE1 JADE2 KAT7 MSX1 MYC NAV2 RELA SUV39H1 TLX3 TP53
Entrez ID		11143	51147
HPRD ID		07135	09774
Ensembl ID		ENSG00000136504	ENSG00000111653
Uniprot IDs		O95251	Q9UNL4
PDB IDs			2K1J 2M1R 2PNX 2VNF 4AFL
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process Mitotic Cell Cycle DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Organelle Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Replication Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA-dependent DNA Replication Negative Regulation Of Biosynthetic Process Neuron Apoptotic Process Regulation Of RNA Metabolic Process Apoptotic Process Neuron Death Programmed Cell Death Regulation Of Transcription, DNA-templated Cell Death Death Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Replication Initiation Regulation Of Cell Cycle Establishment Of Vesicle Localization Vesicle Localization Negative Regulation Of Cellular Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Viral Process Chromosome Organization Regulation Of Cell Cycle Phase Transition Cellular Macromolecule Biosynthetic Process Cellular Process Macromolecule Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of DNA Replication Negative Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Microtubule-based Transport	Chromosome Organization Chromatin Organization Histone H4-K12 Acetylation Histone H4 Acetylation Heterocycle Metabolic Process Histone H4-K5 Acetylation Histone H4-K8 Acetylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Hypoxia Transcription, DNA-templated Cellular Response To Decreased Oxygen Levels Peptidyl-lysine Modification Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Cellular Response To Oxygen Levels Histone Acetylation Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Cellular Nitrogen Compound Metabolic Process Protein Acetylation Chromatin Modification Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Histone H3 Acetylation Cellular Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Macromolecule Biosynthetic Process Histone Modification Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Cellular Response To Nicotine Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Anterior/posterior Pattern Specification
Tagcloud ?		acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently therapeutics throughput tnbc xenografts	aad adenovirus adopted apparently arrested bax bcl blot caspase cleaved cne differential efect g2 measure mtt nasopharyngeal obviously overexpressed p21 pe probable regulating rgd rt survivin synergies vector western
Tagcloud (Difference) ?		acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently therapeutics throughput tnbc xenografts	aad adenovirus adopted apparently arrested bax bcl blot caspase cleaved cne differential efect g2 measure mtt nasopharyngeal obviously overexpressed p21 pe probable regulating rgd rt survivin synergies vector western
Tagcloud (Intersection) ?