KAT7 and DDX11

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KAT7	DDX11
Gene Name		K(lysine) acetyltransferase 7	DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Nucleolus Cytoplasm	Nuclear Chromatin Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Midbody Extracellular Vesicular Exosome
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding	Double-stranded DNA Binding Single-stranded DNA Binding RNA Binding ATP-dependent DNA Helicase Activity Helicase Activity Protein Binding ATP Binding DNA-dependent ATPase Activity Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	DNA Replication Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation	Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Sister Chromatid Cohesion Viral Process Endoplasmic Reticulum Unfolded Protein Response DNA Duplex Unwinding Cellular Protein Metabolic Process
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones	IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN HAP1 HIST1H3A HIST1H4A HIST2H2AC HOOK2 ING4 JADE1 KATNBL1 KCTD13 KIAA1377 LRIF1 MCM2 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPT5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165	2 interactors: KAT7 PFN2
Entrez ID		11143	1663
HPRD ID		07135	03095
Ensembl ID		ENSG00000136504	ENSG00000013573
Uniprot IDs		O95251	Q2NKM7 Q96FC9
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process Mitotic Cell Cycle DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Organelle Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Replication Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA-dependent DNA Replication Negative Regulation Of Biosynthetic Process Neuron Apoptotic Process Regulation Of RNA Metabolic Process Apoptotic Process Neuron Death Programmed Cell Death Regulation Of Transcription, DNA-templated Cell Death Death Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Replication Initiation Regulation Of Cell Cycle Establishment Of Vesicle Localization Vesicle Localization Negative Regulation Of Cellular Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Viral Process Chromosome Organization Regulation Of Cell Cycle Phase Transition Cellular Macromolecule Biosynthetic Process Cellular Process Macromolecule Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of DNA Replication Negative Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Microtubule-based Transport	Negative Regulation Of Ruffle Assembly Histone H4-K12 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Regulation Of Ruffle Assembly Positive Regulation Of ATPase Activity Regulation Of Synaptic Vesicle Exocytosis Regulation Of Synaptic Vesicle Transport Regulation Of ATPase Activity Positive Regulation Of Stress Fiber Assembly Histone H3 Acetylation Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Bundle Assembly Histone H4 Acetylation Regulation Of Stress Fiber Assembly Regulation Of Neurotransmitter Secretion Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation
Tagcloud ?		acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently therapeutics throughput tnbc xenografts	acidophilum chlr1 cpu cyclopurine deoxynucleosides ding distorting dnab fancj helicase helicases impeded ner pigmentosum recq recq1 sf1 sf2 sf4 taxpd thermoplasma translocating unwind unwinding uvrd wrn xeroderma xp xpd
Tagcloud (Difference) ?		acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently therapeutics throughput tnbc xenografts	acidophilum chlr1 cpu cyclopurine deoxynucleosides ding distorting dnab fancj helicase helicases impeded ner pigmentosum recq recq1 sf1 sf2 sf4 taxpd thermoplasma translocating unwind unwinding uvrd wrn xeroderma xp xpd
Tagcloud (Intersection) ?