KAT7 and ZNF165

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KAT7	ZNF165
Description		lysine acetyltransferase 7	zinc finger protein 165
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol Histone H3-K14 Acetyltransferase Complex Site Of DNA Damage	Nucleus
	Molecular Function	Chromatin Binding DNA Replication Origin Binding Transcription Coregulator Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone H3 Acetyltransferase Activity Histone H4 Acetyltransferase Activity Transferase Activity Acyltransferase Activity Histone H3K14 Acetyltransferase Activity Histone H3K23 Acetyltransferase Activity Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Histone H3K4 Acetyltransferase Activity Metal Ion Binding Histone H4K16 Acetyltransferase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Cell Growth Natural Killer Cell Differentiation DNA Replication Regulation Of DNA Replication DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II DNA Damage Response Internal Peptidyl-lysine Acetylation Regulation Of DNA-templated DNA Replication Initiation T Cell Differentiation Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of DNA Replication Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Response To Sorbitol Response To Hydroxyurea Response To Actinomycin D Response To Dithiothreitol Response To Anisomycin DNA Replication-dependent Chromatin Disassembly Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of DNA Biosynthetic Process Regulation Of Nucleotide-excision Repair	Regulation Of Transcription By RNA Polymerase II
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 27863252 29403010) Mean corpuscular volume ( 27863252 29403010) Mean reticulocyte volume ( 32888494)	Apolipoprotein B levels ( 32203549) Appendicular lean mass ( 33097823) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 31451708) Fish- and plant-related diet ( 32066663) HDL cholesterol levels ( 32203549) Hepcidin/ferritin ratio ( 27846281) LDL cholesterol levels ( 32203549) Lung function (FEV1/FVC) ( 30175238) Moderate to vigorous physical activity levels ( 29899525) Refractive error ( 32231278) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Squamous cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		45 interacting genes: APP AR ATN1 BARD1 BGLT3 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP126 CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN H2AC20 H3C1 H4C1 HAP1 HOOK2 ING4 KATNBL1 KCTD13 LRIF1 MAP2K1 MCM2 MCRS1 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPTIN5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165	46 interacting genes: AHCYL1 CARD10 CCDC125 CCDC85B CEP70 DVL2 DVL3 ELOA2 EMD EWSR1 FAM124A GOLGA6L9 GPATCH2L HOMEZ IL16 KAT7 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-12 MAB21L3 MID2 NTAQ1 PDLIM7 PICK1 PLEKHF2 PPL RNPS1 SCAND1 SUV39H1 TRIM41 YJU2B ZKSCAN8 ZNF24 ZNF250 ZNF263 ZNF417 ZNF446 ZNF572 ZNF668 ZNF774 ZNF837
Entrez ID		11143	7718
HPRD ID		07135	02903
Ensembl ID		ENSG00000136504	ENSG00000197279
Uniprot IDs		A0A9L9PXR9 O95251	P49910 Q53Z40
PDB IDs		5GK9 6MAJ 6MAK 7D0O 7D0P 7D0Q 7D0R 7D0S
Enriched GO Terms of Interacting Partners?		DNA Replication Origin Binding Nucleus Regulation Of DNA Metabolic Process DNA Replication Initiation Regulation Of DNA Replication Nuclear Origin Of Replication Recognition Complex Chromatin Organization DNA Metabolic Process DNA Replication Chromatin Remodeling Centrosome Vesicle Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Cytoskeleton Vesicle Cytoskeletal Trafficking Regulation Of Cell Cycle G2/M Phase Transition Chromatin Binding Nucleoplasm Negative Regulation Of DNA Replication Regulation Of Nucleobase-containing Compound Metabolic Process DNA Repair Spindle Pole Regulation Of Cellular Response To Stress Organelle Transport Along Microtubule Transport Along Microtubule Regulation Of Cellular Component Organization Chromosome, Telomeric Region Origin Recognition Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Component Organization Organelle Organization Positive Regulation Of Chromatin Binding Negative Regulation Of Macromolecule Metabolic Process Establishment Of Vesicle Localization Microtubule-based Process Microtubule-based Transport Regulation Of Macromolecule Metabolic Process Protein Heterodimerization Activity Supramolecular Fiber Organization Mitotic DNA Replication Checkpoint Signaling Vesicle Localization Bergmann Glial Cell Differentiation Transcription Coactivator Binding Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Cell Cycle Chromosome Mitotic G2/M Transition Checkpoint Negative Regulation Of Metabolic Process Nuclear Matrix Regulation Of Primary Metabolic Process	Keratin Filament Intermediate Filament Regulation Of RNA Metabolic Process Zinc Ion Binding Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Neuron Projection Arborization Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Neuron Projection Arborization
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