KAT7 and HOOK2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KAT7	HOOK2
Gene Name		K(lysine) acetyltransferase 7	hook microtubule-tethering protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Nucleolus Cytoplasm	Centrosome Microtubule HOPS Complex FHF Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	DNA Replication Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation	Endocytosis Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Early Endosome To Late Endosome Transport
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN HAP1 HIST1H3A HIST1H4A HIST2H2AC HOOK2 ING4 JADE1 KATNBL1 KCTD13 KIAA1377 LRIF1 MCM2 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPT5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165	31 interactors: ABLIM1 AKTIP ANKRD11 ANKRD36BP1 AP1M1 APEX2 CCDC33 CWF19L2 DUSP13 EPS8 FAM107A HOOK1 HOOK3 IQCE ITSN2 KANSL1 KAT7 KIAA0408 MCM10 PSMF1 RALBP1 RIBC2 SUV39H1 USP2 UTP14A UTP14C VPS16 VPS41 ZC2HC1C ZNF250 ZNF638
Entrez ID		11143	29911
HPRD ID		07135	09698
Ensembl ID		ENSG00000136504	ENSG00000095066
Uniprot IDs		O95251	Q96ED9
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process Mitotic Cell Cycle DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Organelle Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Replication Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA-dependent DNA Replication Negative Regulation Of Biosynthetic Process Neuron Apoptotic Process Regulation Of RNA Metabolic Process Apoptotic Process Neuron Death Programmed Cell Death Regulation Of Transcription, DNA-templated Cell Death Death Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Replication Initiation Regulation Of Cell Cycle Establishment Of Vesicle Localization Vesicle Localization Negative Regulation Of Cellular Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Viral Process Chromosome Organization Regulation Of Cell Cycle Phase Transition Cellular Macromolecule Biosynthetic Process Cellular Process Macromolecule Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of DNA Replication Negative Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Microtubule-based Transport	Early Endosome To Late Endosome Transport Vacuolar Transport Endosomal Transport Vacuole Organization Endosome To Lysosome Transport Endosome Organization Lysosomal Transport Regulation Of SNARE Complex Assembly Lysosome Organization Cell Cycle Histone H4-K5 Acetylation Histone H4-K8 Acetylation Organelle Organization RRNA Processing RRNA Metabolic Process Maturation Of SSU-rRNA Cytoplasmic Transport Regulation Of Vesicle Fusion Ribosomal Small Subunit Biogenesis Ribosome Biogenesis Regulation Of Vacuole Fusion, Non-autophagic Vacuole Fusion, Non-autophagic Histone H4 Acetylation Peptidyl-lysine Modification Viral Process Protein Transport Actin Polymerization-dependent Cell Motility Vesicle-mediated Transport Establishment Of Protein Localization
Tagcloud ?		acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently therapeutics throughput tnbc xenografts	accumulated approaches basic benign demonstrates encoding hmga hmga2 initiating leiomyoma leiomyomas limits mesenchymal mobility myometrial opens origin possibilities putative rearrangements side sp stem toward transformation truncated understand uterine work
Tagcloud (Difference) ?		acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently therapeutics throughput tnbc xenografts	accumulated approaches basic benign demonstrates encoding hmga hmga2 initiating leiomyoma leiomyomas limits mesenchymal mobility myometrial opens origin possibilities putative rearrangements side sp stem toward transformation truncated understand uterine work
Tagcloud (Intersection) ?