KAT7 and WDR33

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KAT7	WDR33
Description		lysine acetyltransferase 7	WD repeat domain 33
Image
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol Histone H3-K14 Acetyltransferase Complex Site Of DNA Damage	Fibrillar Center Collagen Trimer Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	Chromatin Binding DNA Replication Origin Binding Transcription Coregulator Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone H3 Acetyltransferase Activity Histone H4 Acetyltransferase Activity Transferase Activity Acyltransferase Activity Histone H3K14 Acetyltransferase Activity Histone H3K23 Acetyltransferase Activity Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Histone H3K4 Acetyltransferase Activity Metal Ion Binding Histone H4K16 Acetyltransferase Activity	RNA Binding
	Biological Process	Regulation Of Cell Growth Natural Killer Cell Differentiation DNA Replication Regulation Of DNA Replication DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II DNA Damage Response Internal Peptidyl-lysine Acetylation Regulation Of DNA-templated DNA Replication Initiation T Cell Differentiation Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of DNA Replication Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Response To Sorbitol Response To Hydroxyurea Response To Actinomycin D Response To Dithiothreitol Response To Anisomycin DNA Replication-dependent Chromatin Disassembly Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of DNA Biosynthetic Process Regulation Of Nucleotide-excision Repair	Postreplication Repair MRNA Processing Spermatogenesis MRNA 3'-end Processing
Pathways		HATs acetylate histones	Transport of Mature mRNA Derived from an Intronless Transcript mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 27863252 29403010) Mean corpuscular volume ( 27863252 29403010) Mean reticulocyte volume ( 32888494)	Coronary artery calcification ( 23870195) Coronary artery disease ( 29212778) White blood cell count ( 32888494)
Interacting Genes		45 interacting genes: APP AR ATN1 BARD1 BGLT3 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP126 CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN H2AC20 H3C1 H4C1 HAP1 HOOK2 ING4 KATNBL1 KCTD13 LRIF1 MAP2K1 MCM2 MCRS1 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPTIN5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165	19 interacting genes: CDK4 EEF1G GIT1 KAT7 MIR19A MIR19B1 MIR34B MIR92A2 PFN2 PRMT1 RBM48 SH3GL3 TGFBR1 TP53 UBC UTP14A WWOX ZBTB16 ZHX1
Entrez ID		11143	55339
HPRD ID		07135	11680
Ensembl ID		ENSG00000136504	ENSG00000136709
Uniprot IDs		A0A9L9PXR9 O95251	Q9C0J8
PDB IDs		5GK9 6MAJ 6MAK 7D0O 7D0P 7D0Q 7D0R 7D0S	6BLY 6BM0 6DNH 6F9N 6FUW 6URG 6URO 8E3I 8E3Q 8R8R
Enriched GO Terms of Interacting Partners?		DNA Replication Origin Binding Nucleus Regulation Of DNA Metabolic Process DNA Replication Initiation Regulation Of DNA Replication Nuclear Origin Of Replication Recognition Complex Chromatin Organization DNA Metabolic Process DNA Replication Chromatin Remodeling Centrosome Vesicle Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Cytoskeleton Vesicle Cytoskeletal Trafficking Regulation Of Cell Cycle G2/M Phase Transition Chromatin Binding Nucleoplasm Negative Regulation Of DNA Replication Regulation Of Nucleobase-containing Compound Metabolic Process DNA Repair Spindle Pole Regulation Of Cellular Response To Stress Organelle Transport Along Microtubule Transport Along Microtubule Regulation Of Cellular Component Organization Chromosome, Telomeric Region Origin Recognition Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Component Organization Organelle Organization Positive Regulation Of Chromatin Binding Negative Regulation Of Macromolecule Metabolic Process Establishment Of Vesicle Localization Microtubule-based Process Microtubule-based Transport Regulation Of Macromolecule Metabolic Process Protein Heterodimerization Activity Supramolecular Fiber Organization Mitotic DNA Replication Checkpoint Signaling Vesicle Localization Bergmann Glial Cell Differentiation Transcription Coactivator Binding Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Cell Cycle Chromosome Mitotic G2/M Transition Checkpoint Negative Regulation Of Metabolic Process Nuclear Matrix Regulation Of Primary Metabolic Process	Regulation Of Extracellular Matrix Assembly Response To Actinomycin D Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cardiac Epithelial To Mesenchymal Transition MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Post-transcriptional Gene Silencing Negative Regulation Of Matrix Metallopeptidase Secretion Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Cell Differentiation Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Cellular Response To Molecule Of Bacterial Origin Negative Regulation Of Developmental Process Regulation Of Extracellular Matrix Organization Regulation Of Heart Growth Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of Extracellular Matrix Assembly Cellular Response To Bacterial Lipopeptide Positive Regulation Of Protein-containing Complex Assembly Regulation Of Cell Growth Response To Bacterial Lipoprotein Negative Regulation Of Fibroblast Migration Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Multicellular Organismal Development Regulation Of Cell Cycle Regulation Of Stem Cell Proliferation RISC Complex Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Organ Growth Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Gene Expression MRNA Destabilization Regulation Of Cell Differentiation RNA Destabilization Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cellular Component Biogenesis Regulation Of Epithelial To Mesenchymal Transition
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