KAT7 and WDR33

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KAT7	WDR33
Gene Name		K(lysine) acetyltransferase 7	WD repeat domain 33
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Nucleolus Cytoplasm	Collagen Trimer Nucleus Nucleoplasm Nucleolus MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding	Poly(A) RNA Binding
	Biological Process	DNA Replication Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation	Postreplication Repair MRNA Polyadenylation MRNA Cleavage Spermatogenesis
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN HAP1 HIST1H3A HIST1H4A HIST2H2AC HOOK2 ING4 JADE1 KATNBL1 KCTD13 KIAA1377 LRIF1 MCM2 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPT5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165	14 interactors: CDK4 EEF1G GIT1 KAT7 PFN2 PRMT1 RBM48 SH3GL3 TGFBR1 TP53 UTP14A WWOX ZBTB16 ZHX1
Entrez ID		11143	55339
HPRD ID		07135	11680
Ensembl ID		ENSG00000136504	ENSG00000136709
Uniprot IDs		O95251	Q9C0J8
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process Mitotic Cell Cycle DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Organelle Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Replication Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA-dependent DNA Replication Negative Regulation Of Biosynthetic Process Neuron Apoptotic Process Regulation Of RNA Metabolic Process Apoptotic Process Neuron Death Programmed Cell Death Regulation Of Transcription, DNA-templated Cell Death Death Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Replication Initiation Regulation Of Cell Cycle Establishment Of Vesicle Localization Vesicle Localization Negative Regulation Of Cellular Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Viral Process Chromosome Organization Regulation Of Cell Cycle Phase Transition Cellular Macromolecule Biosynthetic Process Cellular Process Macromolecule Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of DNA Replication Negative Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Microtubule-based Transport	Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Anterior/posterior Pattern Specification Chromatin Organization System Development Negative Regulation Of Cell Differentiation Developmental Process Positive Regulation Of Cellular Component Biogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Chondrocyte Differentiation Regulation Of Apoptotic Process Nervous System Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cell Death Cell Differentiation Positive Regulation Of Metabolic Process Negative Regulation Of Myeloid Cell Differentiation Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cartilage Development Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process Lens Development In Camera-type Eye Multicellular Organismal Development Regulation Of Cell Cycle Regulation Of Fibroblast Proliferation Regulation Of Cell Cycle Arrest Positive Regulation Of Cellular Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Apoptotic Process Regulation Of Gene Expression Anatomical Structure Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Nitrogen Compound Metabolic Process Programmed Cell Death Negative Regulation Of Cell Cycle Negative Regulation Of Helicase Activity Signal Transduction By P53 Class Mediator Chromosome Organization Regulation Of Cell Projection Assembly Cell Death Death Pattern Specification Process
Tagcloud ?		acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently therapeutics throughput tnbc xenografts
Tagcloud (Difference) ?		acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently therapeutics throughput tnbc xenografts
Tagcloud (Intersection) ?