KAT7 and BGLT3

Number of citations of the paper that reports this interaction (PubMedID 33543443)
0

Data Source:
BioGRID (unspecified method)

		KAT7	BGLT3
Description		lysine acetyltransferase 7	beta globin locus transcript 3
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol Histone H3-K14 Acetyltransferase Complex Site Of DNA Damage
	Molecular Function	Chromatin Binding DNA Replication Origin Binding Transcription Coregulator Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone H3 Acetyltransferase Activity Histone H4 Acetyltransferase Activity Transferase Activity Acyltransferase Activity Histone H3K14 Acetyltransferase Activity Histone H3K23 Acetyltransferase Activity Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Histone H3K4 Acetyltransferase Activity Metal Ion Binding Histone H4K16 Acetyltransferase Activity
	Biological Process	Regulation Of Cell Growth Natural Killer Cell Differentiation DNA Replication Regulation Of DNA Replication DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II DNA Damage Response Internal Peptidyl-lysine Acetylation Regulation Of DNA-templated DNA Replication Initiation T Cell Differentiation Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of DNA Replication Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Response To Sorbitol Response To Hydroxyurea Response To Actinomycin D Response To Dithiothreitol Response To Anisomycin DNA Replication-dependent Chromatin Disassembly Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of DNA Biosynthetic Process Regulation Of Nucleotide-excision Repair
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 27863252 29403010) Mean corpuscular volume ( 27863252 29403010) Mean reticulocyte volume ( 32888494)	Malaria ( 31844061)
Interacting Genes		45 interacting genes: APP AR ATN1 BARD1 BGLT3 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP126 CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN H2AC20 H3C1 H4C1 HAP1 HOOK2 ING4 KATNBL1 KCTD13 LRIF1 MAP2K1 MCM2 MCRS1 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPTIN5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165	7 interacting genes: BARD1 FARP2 KAT7 OTUD3 PARP1 PTEN TBL2
Entrez ID		11143	103344929
HPRD ID		07135
Ensembl ID		ENSG00000136504	ENSG00000260629
Uniprot IDs		A0A9L9PXR9 O95251
PDB IDs		5GK9 6MAJ 6MAK 7D0O 7D0P 7D0Q 7D0R 7D0S
Enriched GO Terms of Interacting Partners?		DNA Replication Origin Binding Nucleus Regulation Of DNA Metabolic Process DNA Replication Initiation Regulation Of DNA Replication Nuclear Origin Of Replication Recognition Complex Chromatin Organization DNA Metabolic Process DNA Replication Chromatin Remodeling Centrosome Vesicle Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Cytoskeleton Vesicle Cytoskeletal Trafficking Regulation Of Cell Cycle G2/M Phase Transition Chromatin Binding Nucleoplasm Negative Regulation Of DNA Replication Regulation Of Nucleobase-containing Compound Metabolic Process DNA Repair Spindle Pole Regulation Of Cellular Response To Stress Organelle Transport Along Microtubule Transport Along Microtubule Regulation Of Cellular Component Organization Chromosome, Telomeric Region Origin Recognition Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Component Organization Organelle Organization Positive Regulation Of Chromatin Binding Negative Regulation Of Macromolecule Metabolic Process Establishment Of Vesicle Localization Microtubule-based Process Microtubule-based Transport Regulation Of Macromolecule Metabolic Process Protein Heterodimerization Activity Supramolecular Fiber Organization Mitotic DNA Replication Checkpoint Signaling Vesicle Localization Bergmann Glial Cell Differentiation Transcription Coactivator Binding Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Cell Cycle Chromosome Mitotic G2/M Transition Checkpoint Negative Regulation Of Metabolic Process Nuclear Matrix Regulation Of Primary Metabolic Process	Protein Modification Process NAD+-histone H3S10 Serine ADP-ribosyltransferase Activity NAD+-histone H2BS6 Serine ADP-ribosyltransferase Activity Site Of DNA Damage NAD+-histone H2BE35 Glutamate ADP-ribosyltransferase Activity Regulation Of DNA Repair Positive Regulation Of DNA-templated Transcription, Elongation Leukocyte Differentiation NAD+-protein-histidine ADP-ribosyltransferase Activity NAD+-protein-tyrosine ADP-ribosyltransferase Activity Intracellular Signal Transduction Negative Regulation Of MRNA 3'-end Processing Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Histone H3K23 Acetyltransferase Activity Histone H3K4 Acetyltransferase Activity Regulation Of DNA Metabolic Process Positive Regulation Of Myofibroblast Differentiation NAD+-protein-serine ADP-ribosyltransferase Activity Regulation Of DNA-templated Transcription Elongation Positive Regulation Of Protein Localization To Nucleus Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Histone H3-K14 Acetyltransferase Complex Response To Dithiothreitol DNA Repair Regulation Of Phosphorus Metabolic Process DNA ADP-ribosylation Negative Regulation Of ATP Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Response To Stress NAD DNA ADP-ribosyltransferase Activity Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission DNA Replication-dependent Chromatin Disassembly Protein K6-linked Deubiquitination Regulation Of Base-excision Repair Myeloid Leukocyte Differentiation ATP Generation From Poly-ADP-D-ribose Response To Ionizing Radiation Signal Transduction BRCA1-B Complex Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Response To Anisomycin Response To Sorbitol
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