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CSNK1E and BID
Number of citations of the paper that reports this interaction (PubMedID
11583622
)
0
Data Source:
HPRD
(in vivo, in vitro)
CSNK1E
BID
Description
casein kinase 1 epsilon
BH3 interacting domain death agonist
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Growth Cone
Neuronal Cell Body
Ribonucleoprotein Complex
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Cytosol
Membrane
Mitochondrial Membrane
Molecular Function
Nucleotide Binding
RNA Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Protein Serine Kinase Activity
Death Receptor Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Cysteine-type Endopeptidase Regulator Activity Involved In Apoptotic Process
Biological Process
DNA Repair
Protein Phosphorylation
Endocytosis
Signal Transduction
Intracellular Protein Localization
Regulation Of Wnt Signaling Pathway
Positive Regulation Of Wnt Signaling Pathway
Negative Regulation Of Wnt Signaling Pathway
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Localization
Circadian Regulation Of Gene Expression
Non-canonical Wnt Signaling Pathway
Regulation Of Circadian Rhythm
Rhythmic Process
Circadian Behavior
Negative Regulation Of Small GTPase Mediated Signal Transduction
Canonical Wnt Signaling Pathway
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Amyloid-beta Formation
Cellular Response To Nerve Growth Factor Stimulus
Positive Regulation Of Non-canonical Wnt Signaling Pathway
Release Of Cytochrome C From Mitochondria
Protein Targeting To Mitochondrion
Apoptotic Process
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Apoptotic Mitochondrial Changes
Positive Regulation Of Mitochondrial Membrane Potential
Positive Regulation Of Protein-containing Complex Assembly
Cellular Response To Stress
Intracellular Signal Transduction
Regulation Of T Cell Proliferation
Signal Transduction In Response To DNA Damage
Mitochondrial ATP Synthesis Coupled Electron Transport
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Regulation Of Epithelial Cell Proliferation
Neuron Apoptotic Process
Protein-containing Complex Assembly
Establishment Of Protein Localization To Membrane
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Extrinsic Apoptotic Signaling Pathway
Hepatocyte Apoptotic Process
Mitochondrial Outer Membrane Permeabilization
Supramolecular Fiber Organization
Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of Intracellular Signal Transduction
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Fibroblast Apoptotic Process
Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
WNT mediated activation of DVL
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
Major pathway of rRNA processing in the nucleolus and cytosol
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A
AURKA Activation by TPX2
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
Activation of BAD and translocation to mitochondria
Activation and oligomerization of BAK protein
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
Activation, translocation and oligomerization of BAX
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Activation, myristolyation of BID and translocation to mitochondria
Drugs
Seliciclib
Umbralisib
Diseases
GWAS
Keratoconus (
31855235
)
Mastocytosis (
32752121
)
Adult body size (
32376654
)
Diisocyanate-induced asthma (
25918132
)
Platelet count (
32888494
)
Plateletcrit (
32888494
)
Interacting Genes
61 interacting genes:
AKAP17A
AKAP9
ANKRD6
APC
APP
ARHGEF1
AXIN1
AXIN2
BBS10
BHLHE41
BID
BMAL1
CADM4
CCDC14
CLOCK
CRY1
CSNK2B
DELEC1
DVL1
DVL2
DVL3
ENTR1
FAM110A
FAM110C
FAM83D
FBP1
FBXO7
FBXW11
GTF3C1
HAUS7
HES1
KAT7
NCOA3
NR1D2
PER1
PER2
PER3
PPP1CA
PPP1CC
PPP1R14A
PPP2R5D
PPP2R5E
PTPRD
RAD17
RAD54B
RBX1
RORA
RORC
SNCA
SOCS3
TAFAZZIN
TAOK1
TLE5
TNS2
TRIM2
TRIM3
WDCP
YAP1
ZMYND8
ZNF227
ZNF618
36 interacting genes:
AHCYL1
BAK1
BAX
BCL2
BCL2A1
BCL2L1
BCL2L2
CAPN1
CAPN2
CASP1
CASP10
CASP2
CASP3
CASP8
CRMP1
CRNKL1
CSNK1A1
CSNK1E
CSNK2A1
CSNK2A2
CSNK2B
DDIT4L
ERG28
FBN3
GAPDH
GBP2
GZMB
MCL1
PLEKHM1
RBM48
REL
SETDB1
TLE1
TUBB2B
YWHAB
ZHX1
Entrez ID
1454
637
HPRD ID
02919
03590
Ensembl ID
ENSG00000213923
ENSG00000015475
Uniprot IDs
P49674
Q5U045
A8ASI8
B2ZP79
B3KT21
P55957
PDB IDs
4HNI
4HOK
1ZY3
2BID
2KBW
2M5B
2M5I
4BD2
4QVE
4ZEQ
4ZIG
4ZII
5AJJ
5C3F
7M5A
7M5B
7P33
7QTW
8SM5
Enriched GO Terms of Interacting Partners
?
Circadian Regulation Of Gene Expression
Regulation Of Circadian Rhythm
Circadian Rhythm
Regulation Of Signal Transduction
Rhythmic Process
Photoperiodism
Regulation Of Cell Communication
Regulation Of Signaling
Entrainment Of Circadian Clock By Photoperiod
Negative Regulation Of Signal Transduction
Entrainment Of Circadian Clock
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Response To Radiation
Negative Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway
Positive Regulation Of Circadian Rhythm
Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Wnt Signaling Pathway
Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of RNA Metabolic Process
E-box Binding
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Regulation Of Cell Cycle
Response To Light Stimulus
Regulation Of Wnt Signaling Pathway
Regulation Of Primary Metabolic Process
Cytoplasm
Signal Transduction
Regulation Of Fat Cell Differentiation
Intracellular Signal Transduction
Negative Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Intracellular Signal Transduction
Transcription Corepressor Binding
Proteasomal Protein Catabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Differentiation
Canonical Wnt Signaling Pathway
Beta-catenin Binding
Positive Regulation Of Neuron Projection Arborization
Negative Regulation Of Wnt Signaling Pathway
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of DNA-templated Transcription
Bcl-2 Family Protein Complex
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Release Of Cytochrome C From Mitochondria
Apoptotic Process
Cell Death
Programmed Cell Death
Channel Activity
Extrinsic Apoptotic Signaling Pathway
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Execution Phase Of Apoptosis
Apoptotic Mitochondrial Changes
Intrinsic Apoptotic Signaling Pathway
BH3 Domain Binding
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Apoptotic Signaling Pathway
Positive Regulation Of Neuron Apoptotic Process
Protein Kinase CK2 Complex
Mitochondrial Outer Membrane
Cysteine-type Peptidase Activity
Regulation Of Apoptotic Process
Protein Maturation
Regulation Of Programmed Cell Death
Identical Protein Binding
Leukocyte Apoptotic Process
DNA Damage Response
Regulation Of Neuron Apoptotic Process
Mitochondrial Fusion
Negative Regulation Of Anoikis
Regulation Of Autophagy
Signal Transduction
Programmed Cell Death Involved In Cell Development
Response To Cytokine
Response To Peptide
Negative Regulation Of Programmed Cell Death
Regulation Of Anoikis
Cysteine-type Endopeptidase Activity
Peptidase Activity
B Cell Homeostasis
Cytosol
Negative Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Pyroptotic Inflammatory Response
Mitochondrion Organization
Regulation Of Proteolysis
Negative Regulation Of Apoptotic Process
Regulation Of Apoptotic Signaling Pathway
Response To Stress
B Cell Apoptotic Process
Pyroptotic Inflammatory Response
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