CSNK1E and ZMYND8

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		CSNK1E	ZMYND8
Gene Name		casein kinase 1, epsilon	zinc finger, MYND-type containing 8
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ribonucleoprotein Complex	Nucleus
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Poly(A) RNA Binding	RNA Polymerase II Transcription Corepressor Activity Protein Binding Zinc Ion Binding Repressing Transcription Factor Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Repair Protein Phosphorylation Endocytosis Organelle Organization Signal Transduction Circadian Rhythm Regulation Of Cell Shape Wnt Signaling Pathway Peptidyl-serine Phosphorylation Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Circadian Regulation Of Gene Expression Cellular Protein Localization Regulation Of Circadian Rhythm Positive Regulation Of Canonical Wnt Signaling Pathway	Negative Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Organelle biogenesis and maintenance misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling G2/M Transition Assembly of the primary cilium Signaling by Wnt Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic WNT mediated activation of DVL Loss of proteins required for interphase microtubule organizationÂ from the centrosome TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation Loss of Nlp from mitotic centrosomes XAV939 inhibits tankyrase, stabilizing AXIN Centrosome maturation Signaling by WNT in cancer Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: AKAP9 ANKRD6 APC APP ARHGEF1 ARNTL AXIN1 AXIN2 BBS10 BID C2orf44 CADM4 CRY1 DVL1 DVL2 DVL3 FAM110A FAM110C FAM83D FBP1 GTF3C1 HES1 KAT7 MCC NCOA3 PER1 PER2 PER3 PNO1 PPP1CA PPP1R14A RAD54B RBX1 SDCCAG3 SOCS3 TAOK1 TAZ TNS2 ZMYND8 ZNF227	9 interactors: ATN1 CSNK1E FHOD1 PBXIP1 PRKCB RERE USP7 ZBTB7A ZFYVE9
Entrez ID		1454	23613
HPRD ID		02919	10166
Ensembl ID		ENSG00000213923	ENSG00000101040
Uniprot IDs		B0QY34 P49674 Q5U045	A6H8Y8 B7Z2A8 B7ZM62 F5H0X3 H7C0U2 J3KPU3 Q2HXV1 Q2HXV3 Q2HXV5 Q569J9 Q9ULU4
PDB IDs		4HNI 4HOK
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Signaling Regulation Of Wnt Signaling Pathway Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Wnt Signaling Pathway Regulation Of Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Circadian Regulation Of Gene Expression Regulation Of Phosphorus Metabolic Process Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Signal Transduction Signal Transduction Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Negative Regulation Of Glucocorticoid Receptor Signaling Pathway Cellular Response To Stimulus Regulation Of Intracellular Signal Transduction Wnt Signaling Pathway Signaling Regulation Of JNK Cascade Circadian Rhythm Cell Communication Canonical Wnt Signaling Pathway Regulation Of Stress-activated MAPK Cascade Planar Cell Polarity Pathway Involved In Neural Tube Closure Cochlea Development Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Positive Regulation Of JNK Cascade Regulation Of Protein Kinase Activity Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Positive Regulation Of Protein Metabolic Process Regulation Of Epithelial Cell Differentiation Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Kinase Activity Regulation Of Cell Differentiation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Stimulus Wnt Signaling Pathway, Planar Cell Polarity Pathway Epithelium Development Positive Regulation Of Metabolic Process Entrainment Of Circadian Clock By Photoperiod	Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Histone H3-T6 Phosphorylation Protein Import Into Nucleus Nuclear Import Chromatin Modification Protein Import Protein Localization To Nucleus Chromatin Organization Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Cellular Process Regulation Of Proteasomal Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Maintenance Of DNA Methylation Heterocycle Metabolic Process SMAD Protein Import Into Nucleus Positive Regulation Of B Cell Receptor Signaling Pathway Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Protein Localization Cellular Nitrogen Compound Metabolic Process Nucleocytoplasmic Transport Nuclear Transport SMAD Protein Complex Assembly Maintenance Of Cell Polarity Toxin Metabolic Process Chromosome Organization Negative Regulation Of Glucose Transport Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Establishment Of Protein Localization To Organelle Transcription, DNA-templated Histone Deubiquitination Lipoprotein Transport NLS-bearing Protein Import Into Nucleus Negative Regulation Of Signaling RNA Biosynthetic Process Regulation Of Protein Catabolic Process Histone Modification
Tagcloud ?		accessible applicable cancerous chosen constitute crc ctnnb1 hct ihc integrated isogenic kill leave lethality msh2 pairs polb ranked rb1 rko rnai sl synergistically therapeutics top tp53 uncovering verified wnt5a
Tagcloud (Difference) ?		accessible applicable cancerous chosen constitute crc ctnnb1 hct ihc integrated isogenic kill leave lethality msh2 pairs polb ranked rb1 rko rnai sl synergistically therapeutics top tp53 uncovering verified wnt5a
Tagcloud (Intersection) ?