CSNK1E and SDCCAG3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CSNK1E	SDCCAG3
Gene Name		casein kinase 1, epsilon	serologically defined colon cancer antigen 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ribonucleoprotein Complex	Endosome Early Endosome Midbody Retromer Complex Recycling Endosome
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Repair Protein Phosphorylation Endocytosis Organelle Organization Signal Transduction Circadian Rhythm Regulation Of Cell Shape Wnt Signaling Pathway Peptidyl-serine Phosphorylation Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Circadian Regulation Of Gene Expression Cellular Protein Localization Regulation Of Circadian Rhythm Positive Regulation Of Canonical Wnt Signaling Pathway	Regulation Of Cytokinesis Retrograde Transport, Endosome To Plasma Membrane
Pathways		Organelle biogenesis and maintenance misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling G2/M Transition Assembly of the primary cilium Signaling by Wnt Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic WNT mediated activation of DVL Loss of proteins required for interphase microtubule organizationÂ from the centrosome TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation Loss of Nlp from mitotic centrosomes XAV939 inhibits tankyrase, stabilizing AXIN Centrosome maturation Signaling by WNT in cancer Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		40 interactors: AKAP9 ANKRD6 APC APP ARHGEF1 ARNTL AXIN1 AXIN2 BBS10 BID C2orf44 CADM4 CRY1 DVL1 DVL2 DVL3 FAM110A FAM110C FAM83D FBP1 GTF3C1 HES1 KAT7 MCC NCOA3 PER1 PER2 PER3 PNO1 PPP1CA PPP1R14A RAD54B RBX1 SDCCAG3 SOCS3 TAOK1 TAZ TNS2 ZMYND8 ZNF227	10 interactors: AP1M1 APP CD99 CHD3 CSNK1E DDX6 GIT1 SDCBP TFPT VIM
Entrez ID		1454	10807
HPRD ID		02919	15307
Ensembl ID		ENSG00000213923	ENSG00000165689
Uniprot IDs		B0QY34 P49674 Q5U045	Q96C92
PDB IDs		4HNI 4HOK
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Signaling Regulation Of Wnt Signaling Pathway Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Wnt Signaling Pathway Regulation Of Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Circadian Regulation Of Gene Expression Regulation Of Phosphorus Metabolic Process Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Signal Transduction Signal Transduction Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Negative Regulation Of Glucocorticoid Receptor Signaling Pathway Cellular Response To Stimulus Regulation Of Intracellular Signal Transduction Wnt Signaling Pathway Signaling Regulation Of JNK Cascade Circadian Rhythm Cell Communication Canonical Wnt Signaling Pathway Regulation Of Stress-activated MAPK Cascade Planar Cell Polarity Pathway Involved In Neural Tube Closure Cochlea Development Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Positive Regulation Of JNK Cascade Regulation Of Protein Kinase Activity Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Positive Regulation Of Protein Metabolic Process Regulation Of Epithelial Cell Differentiation Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Kinase Activity Regulation Of Cell Differentiation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Stimulus Wnt Signaling Pathway, Planar Cell Polarity Pathway Epithelium Development Positive Regulation Of Metabolic Process Entrainment Of Circadian Clock By Photoperiod	Axon Guidance Organelle Organization Ephrin Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Axonogenesis Collateral Sprouting In Absence Of Injury Axon Development Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Extracellular Vesicular Exosome Assembly Chemotaxis Collateral Sprouting Axon Midline Choice Point Recognition Neuron Projection Morphogenesis Movement Of Cell Or Subcellular Component Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Extracellular Vesicular Exosome Assembly Axon Choice Point Recognition Generation Of Neurons Cell Morphogenesis Involved In Differentiation Negative Regulation Of Neuron Differentiation Bergmann Glial Cell Differentiation Neurogenesis Pigment Granule Maturation Endosome To Melanosome Transport Neuron Remodeling Neuron Projection Development Cytoplasmic MRNA Processing Body Assembly Cellular Pigment Accumulation Cell Projection Morphogenesis Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Cell Part Morphogenesis Cell Development Response To External Stimulus Substrate-dependent Cell Migration, Cell Extension
Tagcloud ?		accessible applicable cancerous chosen constitute crc ctnnb1 hct ihc integrated isogenic kill leave lethality msh2 pairs polb ranked rb1 rko rnai sl synergistically therapeutics top tp53 uncovering verified wnt5a
Tagcloud (Difference) ?		accessible applicable cancerous chosen constitute crc ctnnb1 hct ihc integrated isogenic kill leave lethality msh2 pairs polb ranked rb1 rko rnai sl synergistically therapeutics top tp53 uncovering verified wnt5a
Tagcloud (Intersection) ?