TAF8 and KPNA2

Number of citations of the paper that reports this interaction (PMID 15870280)
9

Data Source:
BioGRID (pull down)

		TAF8	KPNA2
Gene Name		TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Perinuclear Region Of Cytoplasm	Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding Protein Heterodimerization Activity	Protein Binding Nuclear Localization Sequence Binding Protein Transporter Activity Histone Deacetylase Binding Poly(A) RNA Binding
	Biological Process	Inner Cell Mass Cell Proliferation Transcription, DNA-templated Cell Differentiation Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Maintenance Of Protein Location In Nucleus	Regulation Of DNA Recombination DNA Metabolic Process NLS-bearing Protein Import Into Nucleus Viral Process Cytokine-mediated Signaling Pathway
Pathways			ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: HIST3H3 KPNA2 KPNB1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF2 TAF4 TAF5 TAF6 TAF7 TAF9 ZDHHC17	104 interactors: ACTN1 ACTN4 ANKIB1 AP2B1 APOBEC1 APP ARL4A ARL5A BRCA1 BTBD2 CASP2 CCDC107 CDA CDK5RAP3 CHD3 CHEK2 CORO1B CREB3L3 CREBBP CSE1L CSNK1A1 CUL4B DCTN2 DDIT3 EP300 EPB41 FEZ2 FN1 FTH1 GART GMCL1 GRB2 H1F0 HAP1 HMG20A HNRNPC HOMER2 HOMEZ HSPA4 IFT20 IMMT INO80E ITK JUN KLC4 KPNB1 KRT18 KRT40 KRT8 LAMB2 LEF1 LZTS2 MAGED1 MAGEH1 MDFI MLH1 MORC3 MVP MYC NECAB2 NFKBIB NMNAT1 NR3C1 NUP153 NUP50 NUP62 NUTM1 PAX5 PLAG1 PNMA5 PRKD3 PTMA RAG1 RAN RANBP2 RBM48 RBPMS RECQL RELA RELB RGL2 RILP RNMT SART3 SERTAD3 SGK1 SLC2A2 SPRY1 SRPK1 TADA2A TAF3 TAF8 TANK TBPL2 TP53 TRAF1 TRIM54 TSC22D4 TXNIP UBR5 USHBP1 ZBTB7B ZC3H12A ZNF131
Entrez ID		129685	3838
HPRD ID		18167	02818
Ensembl ID		ENSG00000137413	ENSG00000182481
Uniprot IDs		B4DZU5 Q7Z7C8	P52292 Q7Z726
PDB IDs			1EFX 1QGK 1QGR 3FEX 3FEY 4E4V
Enriched GO Terms of Interacting Partners?		Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Viral Process Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation RNA Biosynthetic Process Internal Protein Amino Acid Acetylation Protein Acetylation Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Peptidyl-lysine Modification Gene Expression Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Histone H3 Acetylation Histone Modification Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Chromosome Organization Chromatin Modification Chromatin Organization NLS-bearing Protein Import Into Nucleus Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Peptidyl-amino Acid Modification Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Metabolic Process Regulation Of Cellular Process Spermine Transport Positive Regulation Of Transcription, DNA-templated RNA Polymerase II Transcriptional Preinitiation Complex Assembly Protein Import Into Nucleus Nuclear Import Positive Regulation Of Transcription From RNA Polymerase II Promoter	Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Cellular Process RNA Biosynthetic Process Gene Expression Response To Stimulus Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Cell Death Death Apoptotic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process Programmed Cell Death Viral Process Organelle Organization Regulation Of Nucleic Acid-templated Transcription Signal Transduction Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Developmental Process Regulation Of Transcription, DNA-templated Signaling Positive Regulation Of Transcription, DNA-templated Protein Localization To Nucleus Macromolecule Biosynthetic Process Cellular Localization Cell Cycle Negative Regulation Of Biosynthetic Process Cell Communication Negative Regulation Of Nucleic Acid-templated Transcription Cellular Process Negative Regulation Of RNA Biosynthetic Process Cell Cycle Process Response To Stress Positive Regulation Of Gene Expression Nucleocytoplasmic Transport Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Transcription, DNA-templated Nuclear Transport Positive Regulation Of Macromolecule Biosynthetic Process Multicellular Organismal Development
Tagcloud ?			aggressive aggressiveness assembled attempt carcinomas curable diagnostics disregarding eic emgd endometrial entities figo immunoreactivity interplay introducing malignancy mediator mfe microarrays nucleocytoplasmic precancerous regimens surgically tmas trp53 tumour untreatable uterus
Tagcloud (Difference) ?			aggressive aggressiveness assembled attempt carcinomas curable diagnostics disregarding eic emgd endometrial entities figo immunoreactivity interplay introducing malignancy mediator mfe microarrays nucleocytoplasmic precancerous regimens surgically tmas trp53 tumour untreatable uterus
Tagcloud (Intersection) ?