TAF8 and TAF2

Number of citations of the paper that reports this interaction (PubMedID 14580349)
0

Data Source:
HPRD (in vivo, in vitro)

		TAF8	TAF2
Description		TATA-box binding protein associated factor 8	TATA-box binding protein associated factor 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex
	Molecular Function	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity	Transcription Cis-regulatory Region Binding Chromatin Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity
	Biological Process	DNA-templated Transcription Open Complex Formation Inner Cell Mass Cell Proliferation Transcription Initiation At RNA Polymerase II Promoter Cell Differentiation MRNA Transcription By RNA Polymerase II Regulation Of Fat Cell Differentiation RNA Polymerase II Preinitiation Complex Assembly Maintenance Of Protein Location In Nucleus Positive Regulation Of Transcription Initiation By RNA Polymerase II	G2/M Transition Of Mitotic Cell Cycle Regulation Of DNA Repair Regulation Of Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Response To Paraquat
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (number of eye fixations) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (responsive search score) ( 26242244) HDL cholesterol levels ( 28334899) Hemoglobin levels ( 33491795) Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Neutrophil percentage of white cells ( 32888494)	Heart rate response to exercise ( 29769521)
Interacting Genes		13 interacting genes: H3-4 KPNA2 KPNB1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF7 TAF9	14 interacting genes: ESR1 H3-4 PUF60 TAF1 TAF10 TAF11 TAF12 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 UBC
Entrez ID		129685	6873
HPRD ID		18167	07060
Ensembl ID		ENSG00000137413	ENSG00000064313
Uniprot IDs		A0A8I5KXI2 A0A8I5QL44 Q7Z7C8	A0A8I5KSY6 A0A8I5KV60 A0A8I5QJR0 B3KMD8 Q6P1X5
PDB IDs		4WV4 4WV6 5FUR 6MZC 6MZL 6MZM 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGG 7EGH 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS	5FUR 6MZC 6MZL 6MZM 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGH 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS
Enriched GO Terms of Interacting Partners?		Transcription Factor TFIID Complex RNA Polymerase II General Transcription Initiation Factor Activity MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly MRNA Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Transcription Factor TFTC Complex Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase II Promoter Protein-DNA Complex Assembly Transcription By RNA Polymerase II DNA-templated Transcription Regulation Of DNA Repair MRNA Metabolic Process Protein-containing Complex Assembly Protein-containing Complex Organization MLL1 Complex Regulation Of DNA Metabolic Process Protein Heterodimerization Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleobase-containing Compound Biosynthetic Process Positive Regulation Of RNA Metabolic Process Cellular Component Assembly Positive Regulation Of Nucleobase-containing Compound Metabolic Process SAGA Complex Regulation Of Cellular Response To Stress Positive Regulation Of Transcription By RNA Polymerase II RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process Positive Regulation Of Biosynthetic Process Nucleoplasm Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process TBP-class Protein Binding Histone Acetyltransferase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Male Germ Cell Nucleus Aryl Hydrocarbon Receptor Binding	RNA Polymerase II Preinitiation Complex Assembly Transcription Factor TFIID Complex Transcription Preinitiation Complex Assembly RNA Polymerase II General Transcription Initiation Factor Activity MRNA Transcription By RNA Polymerase II MRNA Transcription Protein-DNA Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase II Promoter Transcription Factor TFTC Complex Transcription By RNA Polymerase II DNA-templated Transcription Protein-containing Complex Assembly MRNA Metabolic Process Protein-containing Complex Organization Protein Heterodimerization Activity Nucleobase-containing Compound Biosynthetic Process RNA Metabolic Process MLL1 Complex Positive Regulation Of Transcription By RNA Polymerase II Cellular Component Assembly Regulation Of DNA Repair Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process Nucleoplasm Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription SAGA Complex TBP-class Protein Binding Positive Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA Metabolic Process Regulation Of Cellular Response To Stress Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Nucleus Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone Acetyltransferase Activity Positive Regulation Of Metabolic Process
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