COL8A1 and VAC14

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		COL8A1	VAC14
Gene Name		collagen, type VIII, alpha 1	Vac14 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Type VIII Trimer Endoplasmic Reticulum Lumen Extracellular Matrix Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Golgi Membrane Endoplasmic Reticulum Endosome Membrane Early Endosome Membrane Late Endosome Membrane PAS Complex
	Molecular Function		Receptor Activity Protein Binding
	Biological Process	Angiogenesis Cell Adhesion Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Endodermal Cell Differentiation Camera-type Eye Morphogenesis Epithelial Cell Proliferation	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Signal Transduction Viral Process Regulation Of Lipid Kinase Activity Small Molecule Metabolic Process
Pathways		Collagen formation Collagen degradation Integrin cell surface interactions Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures	Phospholipid metabolism Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Synthesis of PIPs at the late endosome membrane Metabolism Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Synthesis of PIPs at the early endosome membrane PI Metabolism Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS		Age-related macular degeneration ( 20385826 23455636)
Protein-Protein Interactions		20 interactors: ADAMTSL4 COL8A2 CREB5 EFEMP2 INCA1 ITGA1 ITGA2 KLHL12 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP26-1 KRTAP4-12 KRTAP9-2 NOTCH2NL REL SP4 UBQLN4 VAC14	47 interactors: ACSS1 APP ASB13 BHLHE40 C11orf54 C4orf33 CASP1 CCBL1 CCDC103 CD209 CDRT4 CNTN2 COL8A1 DDAH2 FIG4 FNDC3B JMJD7 KRTAP19-5 KRTAP19-7 LINC00518 LPAL2 MGAT5B MPPED2 MTMR9 MVP NGB NOS1 PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PRADC1 PRR13 PRR20A RBFOX2 RHOXF2 SIGLEC5 SMUG1 SNF8 SPRYD7 TCEANC TP53BP1 WDYHV1 ZNF34
Entrez ID		1295	55697
HPRD ID		00372	07660
Ensembl ID		ENSG00000144810	ENSG00000103043
Uniprot IDs		P27658	Q08AM6 Q9NTB8
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Phosphatase Activity Positive Regulation Of Dephosphorylation Positive Regulation Of Collagen Binding	Arginine Catabolic Process Nitric Oxide Biosynthetic Process Nitric Oxide Mediated Signal Transduction Arginine Metabolic Process Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Phosphatidylinositol-3-phosphate Biosynthetic Process Nitric Oxide Metabolic Process Cellular Amino Acid Catabolic Process Cell Recognition Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Neuron Maturation Myelin Assembly Second-messenger-mediated Signaling Myelination Neuron Recognition Axon Ensheathment
Tagcloud ?		bladder carcinogenic deregulation elucidates emodin epigenetic epigenetics fabp4 h3k27 h3k27me3 h3s10 hbp17 inc periodicals ph3ser10 rational repressed restore reverses reversing rgs4 situations specialized timp3 urb viii warrants wiley wnt5b	abundance alleles biosynthesis charcot conditional dependence discovery endolysosomal fab1 fig4 highlights insight knockouts learned macromolecular manipulating marie neurological p2 p2in pi pikfyve spontaneous summarizes tooth turnover utility varon yunis
Tagcloud (Difference) ?		bladder carcinogenic deregulation elucidates emodin epigenetic epigenetics fabp4 h3k27 h3k27me3 h3s10 hbp17 inc periodicals ph3ser10 rational repressed restore reverses reversing rgs4 situations specialized timp3 urb viii warrants wiley wnt5b	abundance alleles biosynthesis charcot conditional dependence discovery endolysosomal fab1 fig4 highlights insight knockouts learned macromolecular manipulating marie neurological p2 p2in pi pikfyve spontaneous summarizes tooth turnover utility varon yunis
Tagcloud (Intersection) ?