COL8A1 and COL8A2

Number of citations of the paper that reports this interaction (PMID 12782141)
10

Data Source:
HPRD (in vitro)

		COL8A1	COL8A2
Gene Name		collagen, type VIII, alpha 1	collagen, type VIII, alpha 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Type VIII Trimer Endoplasmic Reticulum Lumen Extracellular Matrix Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Extracellular Region Proteinaceous Extracellular Matrix Collagen Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function		Extracellular Matrix Structural Constituent Protein Binding, Bridging
	Biological Process	Angiogenesis Cell Adhesion Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Endodermal Cell Differentiation Camera-type Eye Morphogenesis Epithelial Cell Proliferation	Angiogenesis Single Organismal Cell-cell Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Camera-type Eye Morphogenesis Epithelial Cell Proliferation
Pathways		Collagen formation Collagen degradation Integrin cell surface interactions Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures	Collagen formation Collagen degradation Integrin cell surface interactions Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS		Age-related macular degeneration ( 20385826 23455636)	Corneal structure ( 23291589)
Protein-Protein Interactions		20 interactors: ADAMTSL4 COL8A2 CREB5 EFEMP2 INCA1 ITGA1 ITGA2 KLHL12 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP26-1 KRTAP4-12 KRTAP9-2 NOTCH2NL REL SP4 UBQLN4 VAC14	2 interactors: COL8A1 SGTA
Entrez ID		1295	1296
HPRD ID		00372	08347
Ensembl ID		ENSG00000144810	ENSG00000171812
Uniprot IDs		P27658	E9PP49 P25067
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Phosphatase Activity Positive Regulation Of Dephosphorylation Positive Regulation Of Collagen Binding	Endodermal Cell Differentiation Endoderm Formation Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Endoderm Development Epithelial Cell Proliferation Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Positive Regulation Of Cell-substrate Adhesion Camera-type Eye Morphogenesis Formation Of Primary Germ Layer
Tagcloud ?		bladder carcinogenic deregulation elucidates emodin epigenetic epigenetics fabp4 h3k27 h3k27me3 h3s10 hbp17 inc periodicals ph3ser10 rational repressed restore reverses reversing rgs4 situations specialized timp3 urb viii warrants wiley wnt5b	acetylcysteine bl6 blotting c57 celltiter chop confocal corneal drinking dystrophy endothelial endothelium fecd fuchs glo grp78 h2o2 homozygous ingestion inos knock l450w luminescent nac polymegathism reagent thapsigargin unfolded untreated
Tagcloud (Difference) ?		bladder carcinogenic deregulation elucidates emodin epigenetic epigenetics fabp4 h3k27 h3k27me3 h3s10 hbp17 inc periodicals ph3ser10 rational repressed restore reverses reversing rgs4 situations specialized timp3 urb viii warrants wiley wnt5b	acetylcysteine bl6 blotting c57 celltiter chop confocal corneal drinking dystrophy endothelial endothelium fecd fuchs glo grp78 h2o2 homozygous ingestion inos knock l450w luminescent nac polymegathism reagent thapsigargin unfolded untreated
Tagcloud (Intersection) ?