MATN2 and CBFA2T3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		MATN2	CBFA2T3
Gene Name		matrilin 2	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Basement Membrane Extracellular Matrix	Golgi Membrane Nucleus Nucleoplasm Nucleolus
	Molecular Function	Molecular_function Calcium Ion Binding Protein Binding	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Neuron Migration Axon Guidance Biological_process Glial Cell Migration Dendrite Regeneration Response To Axon Injury	Transcription, DNA-templated Cell Proliferation Granulocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
Protein-Protein Interactions		18 interactors: ATXN1 ATXN1L ATXN7 CACNA1A CBFA2T3 COL1A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 DVL3 FBN2 FN1 MATN1 MATN3 MATN4	14 interactors: CBFA2T2 GMEB2 HDAC1 HDAC3 MATN2 PRKAR2A RUNX1 RUNX1T1 SEC24A TCF3 ZBTB33 ZBTB38 ZBTB4 ZNF652
Entrez ID		4147	863
HPRD ID		03660	04847
Ensembl ID		ENSG00000132561	ENSG00000129993
Uniprot IDs		O00339 Q8N2G3	O75081
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Disassembly Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process System Development Multicellular Organismal Development Cell Morphogenesis Involved In Differentiation Anatomical Structure Development Developmental Process Anatomical Structure Morphogenesis Cell Morphogenesis Organ Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Morphogenesis Axon Guidance Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Neuron Projection Development Locomotion Cell Development Cell Projection Morphogenesis Cell Part Morphogenesis Bone Trabecula Formation Axonogenesis Cell Differentiation Neuron Development Axon Development Movement Of Cell Or Subcellular Component Chemotaxis Glomerular Basement Membrane Development Anatomical Structure Formation Involved In Morphogenesis Generation Of Neurons Bone Trabecula Morphogenesis Neuron Differentiation Neurogenesis Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cell Projection Organization Catabolic Process Response To External Stimulus Synapse Organization Cardiovascular System Development Cartilage Development Involved In Endochondral Bone Morphogenesis Endodermal Cell Differentiation Blood Vessel Development Vasculature Development Trabecula Morphogenesis Skeletal System Development Neuromuscular Junction Development	Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Receptor Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Histone H4 Deacetylation Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Histone H3 Deacetylation Histone H3-K9 Modification Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Positive Regulation Of Cellular Metabolic Process Skin Development Response To Growth Factor Dendrite Regeneration Histone Deacetylation Protein Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Circadian Regulation Of Gene Expression Positive Regulation Of Progesterone Secretion Cellular Metabolic Process
Tagcloud ?		amplifiable analyte angpt2 aptamer c7 cdta clostridium crdl1 difficile du exponential gpvi hold lumavidin luminex multiplexed naphthylmethyl panels picomolar plg radiolabel reagents sandwich selex somamer somamers tryptaminocarbonyl tsp2 wise	7q amotl1 cn crebbp cul1 directory exome expanding expands fat4 fbxo11 flnc ighv1 integrating map3k14 minimally mll2 notch2 pla2g4d positioned recurrently silent smzl spen splenic tnfaip3 trrap ush2a wes
Tagcloud (Difference) ?		amplifiable analyte angpt2 aptamer c7 cdta clostridium crdl1 difficile du exponential gpvi hold lumavidin luminex multiplexed naphthylmethyl panels picomolar plg radiolabel reagents sandwich selex somamer somamers tryptaminocarbonyl tsp2 wise	7q amotl1 cn crebbp cul1 directory exome expanding expands fat4 fbxo11 flnc ighv1 integrating map3k14 minimally mll2 notch2 pla2g4d positioned recurrently silent smzl spen splenic tnfaip3 trrap ush2a wes
Tagcloud (Intersection) ?