MATN2 and MATN1

Number of citations of the paper that reports this interaction (PubMedID 11896063)
0

Data Source:
HPRD (in vitro)

		MATN2	MATN1
Description		matrilin 2	matrilin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Matrix Matrilin Complex	Extracellular Region Extracellular Matrix Matrilin Complex
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding
	Biological Process	Neuron Migration Axon Guidance Glial Cell Migration Extracellular Matrix Organization Dendrite Regeneration Neuron Projection Development Response To Axon Injury	Chondrocyte Differentiation Growth Plate Cartilage Chondrocyte Morphogenesis Extracellular Matrix Organization Regulation Of Bone Mineralization Protein-containing Complex Assembly
Pathways			ECM proteoglycans
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Diffusing capacity of carbon monoxide ( 30694715) Eosinophilic esophagitis ( 34506852) Erectile dysfunction ( 30583798)	Broad depression or schizophrenia ( 30626913) Low high density lipoprotein cholesterol levels ( 26879886) Monocyte count ( 32888494) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Schizophrenia ( 28991256 30285260) Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		17 interacting genes: ATXN1 ATXN1L ATXN7 CACNA1A CBFA2T3 COL1A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 DVL3 FBN2 FN1 MATN1 MATN4	5 interacting genes: COL2A1 ITGA1 MATN2 MATN3 MATN4
Entrez ID		4147	4146
HPRD ID		03660	00276
Ensembl ID		ENSG00000132561	ENSG00000162510
Uniprot IDs		A0A140VKH7 O00339 Q8N2G3	P21941
PDB IDs
Enriched GO Terms of Interacting Partners?		Collagen Type IV Trimer Extracellular Matrix Structural Constituent Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Collagen-activated Signaling Pathway Extracellular Matrix Structural Constituent Conferring Tensile Strength Extracellular Matrix Extracellular Matrix Organization Extracellular Structure Organization Collagen Trimer Basement Membrane Endoplasmic Reticulum Lumen Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Extracellular Region Enzyme-linked Receptor Protein Signaling Pathway Matrilin Complex POZ Domain Binding Bone Trabecula Formation Cell Surface Receptor Signaling Pathway Platelet-derived Growth Factor Binding Glomerular Basement Membrane Development Cellular Response To Amino Acid Stimulus Protease Binding Response To Amino Acid Endodermal Cell Differentiation Neuromuscular Junction Development DNA-templated Transcription Cellular Response To Vitamin E Anatomical Structure Formation Involved In Morphogenesis Growth Plate Cartilage Chondrocyte Morphogenesis Lung Alveolus Development Regulation Of Developmental Process Nervous System Process Social Behavior Brain Development Animal Organ Development Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Multicellular Organismal Development Collagen Type I Trimer Cellular Response To Fluoride Response To Transforming Growth Factor Beta Response To Activity Regulation Of Bone Mineralization Developmental Process Sequestering Of TGFbeta In Extracellular Matrix Negative Regulation Of Monocyte Activation Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Signal Transduction Angiogenesis Response To Fluoride Calcium-independent Cell-matrix Adhesion	Matrilin Complex Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Extracellular Matrix Structural Constituent Basement Membrane Cartilage Development Integrin Alpha1-beta1 Complex Dendrite Regeneration Calcium Ion Binding Collagen Type II Trimer Lactose Synthase Activity Collagen Type XI Trimer Skeletal System Development Anterior Head Development Collagen Binding Involved In Cell-matrix Adhesion N-acetyllactosamine Synthase Activity Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity MHC Class II Protein Binding Phosphatase Activator Activity Galactosyltransferase Activity Otic Vesicle Development Extracellular Region Fibrillar Collagen Trimer Limb Bud Formation Notochord Development Platelet-derived Growth Factor Binding Cerebellar Purkinje Cell Layer Development Embryonic Skeletal Joint Morphogenesis Endoplasmic Reticulum Lumen Proteoglycan Binding Basal Part Of Cell Cellular Extravasation Cartilage Condensation Cartilage Development Involved In Endochondral Bone Morphogenesis
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