MATN2 and MATN4

Number of citations of the paper that reports this interaction (PubMedID 11896063)
0

Data Source:
HPRD (in vitro)

		MATN2	MATN4
Description		matrilin 2	matrilin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Matrix Matrilin Complex	Extracellular Region Extracellular Matrix Matrilin Complex
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Neuron Migration Axon Guidance Glial Cell Migration Extracellular Matrix Organization Dendrite Regeneration Neuron Projection Development Response To Axon Injury	Extracellular Matrix Organization
Pathways			ECM proteoglycans
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Diffusing capacity of carbon monoxide ( 30694715) Eosinophilic esophagitis ( 34506852) Erectile dysfunction ( 30583798)	Blood protein levels ( 30072576) Malaria ( 31844061)
Interacting Genes		17 interacting genes: ATXN1 ATXN1L ATXN7 CACNA1A CBFA2T3 COL1A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 DVL3 FBN2 FN1 MATN1 MATN4	9 interacting genes: ACSF3 ENKD1 GORASP2 MATN1 MATN2 MATN3 NTAQ1 PPP1R13B SDCBP
Entrez ID		4147	8785
HPRD ID		03660	04873
Ensembl ID		ENSG00000132561	ENSG00000124159
Uniprot IDs		A0A140VKH7 O00339 Q8N2G3	A2RRP8 A5D8U1 A6NNA4 B3KQB2 O95460
PDB IDs
Enriched GO Terms of Interacting Partners?		Collagen Type IV Trimer Extracellular Matrix Structural Constituent Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Collagen-activated Signaling Pathway Extracellular Matrix Structural Constituent Conferring Tensile Strength Extracellular Matrix Extracellular Matrix Organization Extracellular Structure Organization Collagen Trimer Basement Membrane Endoplasmic Reticulum Lumen Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Extracellular Region Enzyme-linked Receptor Protein Signaling Pathway Matrilin Complex POZ Domain Binding Bone Trabecula Formation Cell Surface Receptor Signaling Pathway Platelet-derived Growth Factor Binding Glomerular Basement Membrane Development Cellular Response To Amino Acid Stimulus Protease Binding Response To Amino Acid Endodermal Cell Differentiation Neuromuscular Junction Development DNA-templated Transcription Cellular Response To Vitamin E Anatomical Structure Formation Involved In Morphogenesis Growth Plate Cartilage Chondrocyte Morphogenesis Lung Alveolus Development Regulation Of Developmental Process Nervous System Process Social Behavior Brain Development Animal Organ Development Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Multicellular Organismal Development Collagen Type I Trimer Cellular Response To Fluoride Response To Transforming Growth Factor Beta Response To Activity Regulation Of Bone Mineralization Developmental Process Sequestering Of TGFbeta In Extracellular Matrix Negative Regulation Of Monocyte Activation Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Signal Transduction Angiogenesis Response To Fluoride Calcium-independent Cell-matrix Adhesion	Matrilin Complex Extracellular Matrix Structural Constituent Extracellular Structure Organization Growth Plate Cartilage Chondrocyte Morphogenesis Extracellular Matrix Organization Interleukin-5 Receptor Complex Protein-N-terminal Glutamine Amidohydrolase Activity Malonyl-CoA Synthetase Activity Malonate Catabolic Process Extracellular Matrix Dendrite Regeneration Interleukin-5 Receptor Binding Protein-N-terminal Asparagine Amidohydrolase Activity Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding
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