LRRK2 and SH3GL2

  • Number of citations of the paper that reports this interaction (PMID 22998870)
  • 28
  • Data Source:
  • BioGRID (enzymatic study)

LRRK2

SH3GL2

Gene Name leucine-rich repeat kinase 2 SH3-domain GRB2-like 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 33 interactors: ACTB AKT1 ARFGAP1 ARHGEF7 BAG5 DVL1 DVL2 DVL3 EIF4EBP1 HSPD1 L3MBTL3 LRP6 MAP1B MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAPT MBP PRKCZ PTPN23 RALYL RIPK2 SH3GL1 SH3GL2 SH3GL3 STK24 STK25 STK3 STRBP TAOK3 TRAF2 TUBA1A 53 interactors: ACTG1 ADAM15 ADAM19 ADRB1 AMPH APP ARNT2 ATXN2 BIN1 CD2AP CLEC3B DACT1 DLGAP4 DNM1 DNM2 DPPA4 DPYSL4 EGFL6 EMD ERH F13A1 GCH1 GSTM3 HLA-DQA1 IGHM IL6 ITCH ITSN1 LCP2 LRRK2 MAP4K3 MAST2 PAK2 PAXIP1 PDCD6IP PPP1R21 PPP6R1 PRR14 SH3GL1 SH3GL3 SH3KBP1 SLC17A7 SYN1 SYNJ1 SYNJ2 TCEA2 TERF1 TIAM2 TMEM108 TYMS ZNF219 ZNF580 ZXDC
Entrez ID 120892 6456
HPRD ID 10613 05125
Ensembl ID ENSG00000188906 ENSG00000107295
Uniprot IDs Q17RV3 Q5S007 B7Z7W3 F5H5J3 Q7Z376 Q8IZ09 Q99962
PDB IDs 2ZEJ 3D6T 1X03 1X04 2D4C 2DBM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
autosomal  decline  difficulty  dj1  england  g2019s  gait  gu  hoehn  idiopathic  leucine  motor  movement  parkinson  pd  pigd  pink1  postural  prkn  rating  schwab  snca  society  staging  udrs  undefined  unified  updrs  yahr 
250k  9p22  affymetrix  alteration  array  biopsies  corresponding  deleted  evident  forced  heterozygosity  informative  interactor  internalization  invasion  modulating  mucosal  nsclc  nspi  paired  platform  scanning  ser  ss  transfected  tyr  understand  usp9x  validation 
Tagcloud (Difference) ?
autosomal  decline  difficulty  dj1  england  g2019s  gait  gu  hoehn  idiopathic  leucine  motor  movement  parkinson  pd  pigd  pink1  postural  prkn  rating  schwab  snca  society  staging  udrs  undefined  unified  updrs  yahr 
250k  9p22  affymetrix  alteration  array  biopsies  corresponding  deleted  evident  forced  heterozygosity  informative  interactor  internalization  invasion  modulating  mucosal  nsclc  nspi  paired  platform  scanning  ser  ss  transfected  tyr  understand  usp9x  validation 
Tagcloud (Intersection) ?