LRRK2 and DVL1

  • Number of citations of the paper that reports this interaction (PMID 19625296)
  • 24
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)

LRRK2

DVL1

Gene Name leucine-rich repeat kinase 2 dishevelled segment polarity protein 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 33 interactors: ACTB AKT1 ARFGAP1 ARHGEF7 BAG5 DVL1 DVL2 DVL3 EIF4EBP1 HSPD1 L3MBTL3 LRP6 MAP1B MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAPT MBP PRKCZ PTPN23 RALYL RIPK2 SH3GL1 SH3GL2 SH3GL3 STK24 STK25 STK3 STRBP TAOK3 TRAF2 TUBA1A 35 interactors: ANXA7 ARRB1 ATN1 AXIN1 BRD7 CCDC88C CSNK1D CSNK1E CSNK2A1 CTNNB1 CXXC4 DAAM1 DAB2 DVL3 DYNLT1 EPS8 FRAT1 HDHD2 HECW1 LRRK2 NCK2 NEDD4 PPM1A PSMA3 RAC1 SIPA1 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 TRIM69 USP13 VANGL1 VANGL2
Entrez ID 120892 1855
HPRD ID 10613 03220
Ensembl ID ENSG00000188906 ENSG00000107404
Uniprot IDs Q17RV3 Q5S007 O14640 Q86TH3
PDB IDs 2ZEJ 3D6T
Enriched GO Terms of Interacting Partners?
Tagcloud ?
autosomal  decline  difficulty  dj1  england  g2019s  gait  gu  hoehn  idiopathic  leucine  motor  movement  parkinson  pd  pigd  pink1  postural  prkn  rating  schwab  snca  society  staging  udrs  undefined  unified  updrs  yahr 
1p36  1q36  20p12  2q37  accumulating  boy  brachydactyly  chr1  chr2  chr20  cnv  cnvs  coarctation  deleted  deletion  digit  duplications  dysmorphism  facial  gpcpd1  hdac4  intellectual  malformations  p36  pcrs  phenotypes  simply  syndromic  tumorigenic 
Tagcloud (Difference) ?
autosomal  decline  difficulty  dj1  england  g2019s  gait  gu  hoehn  idiopathic  leucine  motor  movement  parkinson  pd  pigd  pink1  postural  prkn  rating  schwab  snca  society  staging  udrs  undefined  unified  updrs  yahr 
1p36  1q36  20p12  2q37  accumulating  boy  brachydactyly  chr1  chr2  chr20  cnv  cnvs  coarctation  deleted  deletion  digit  duplications  dysmorphism  facial  gpcpd1  hdac4  intellectual  malformations  p36  pcrs  phenotypes  simply  syndromic  tumorigenic 
Tagcloud (Intersection) ?