LRRK2 and MAP2K4

  • Number of citations of the paper that reports this interaction (PMID 19302196)
  • 47
  • Data Source:
  • BioGRID (enzymatic study)

LRRK2

MAP2K4

Gene Name leucine-rich repeat kinase 2 mitogen-activated protein kinase kinase 4
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 33 interactors: ACTB AKT1 ARFGAP1 ARHGEF7 BAG5 DVL1 DVL2 DVL3 EIF4EBP1 HSPD1 L3MBTL3 LRP6 MAP1B MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAPT MBP PRKCZ PTPN23 RALYL RIPK2 SH3GL1 SH3GL2 SH3GL3 STK24 STK25 STK3 STRBP TAOK3 TRAF2 TUBA1A 37 interactors: AKT1 APP ARRB1 ARRB2 CFLAR DUSP22 EFNA4 FLNA FLNC GEMIN5 ITCH JUN LRRK2 MAP2K6 MAP3K1 MAP3K10 MAP3K11 MAP3K12 MAP3K14 MAP3K2 MAP3K3 MAP3K4 MAP3K5 MAP3K7 MAP3K8 MAP4K2 MAPK1 MAPK10 MAPK12 MAPK14 MAPK8 MAPK8IP3 MAPK9 RBBP8 SPAG9 TRIB1 ZAK
Entrez ID 120892 6416
HPRD ID 10613 03213
Ensembl ID ENSG00000188906 ENSG00000065559
Uniprot IDs Q17RV3 Q5S007 B7ZA62 P45985
PDB IDs 2ZEJ 3D6T 3ALN 3ALO 3VUT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
autosomal  decline  difficulty  dj1  england  g2019s  gait  gu  hoehn  idiopathic  leucine  motor  movement  parkinson  pd  pigd  pink1  postural  prkn  rating  schwab  snca  society  staging  udrs  undefined  unified  updrs  yahr 
aurka  aurkb  bioinformatics  cdkn2a  copy  custom  describing  epha5  flt4  frameshift  insertions  interrogating  kdm6a  leiomyosarcomas  locally  losses  multiplexed  nf1  ngs  notch1  pdgfrb  pik3ca  pipeline  rationale  rb1  sarcomas  soft  stratification  targetable 
Tagcloud (Difference) ?
autosomal  decline  difficulty  dj1  england  g2019s  gait  gu  hoehn  idiopathic  leucine  motor  movement  parkinson  pd  pigd  pink1  postural  prkn  rating  schwab  snca  society  staging  udrs  undefined  unified  updrs  yahr 
aurka  aurkb  bioinformatics  cdkn2a  copy  custom  describing  epha5  flt4  frameshift  insertions  interrogating  kdm6a  leiomyosarcomas  locally  losses  multiplexed  nf1  ngs  notch1  pdgfrb  pik3ca  pipeline  rationale  rb1  sarcomas  soft  stratification  targetable 
Tagcloud (Intersection) ?