LRRK2 and MAP2K6

  • Number of citations of the paper that reports this interaction (PMID 20067578)
  • 22
  • Data Source:
  • BioGRID (enzymatic study)

LRRK2

MAP2K6

Gene Name leucine-rich repeat kinase 2 mitogen-activated protein kinase kinase 6
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225)
Protein-Protein Interactions 33 interactors: ACTB AKT1 ARFGAP1 ARHGEF7 BAG5 DVL1 DVL2 DVL3 EIF4EBP1 HSPD1 L3MBTL3 LRP6 MAP1B MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAPT MBP PRKCZ PTPN23 RALYL RIPK2 SH3GL1 SH3GL2 SH3GL3 STK24 STK25 STK3 STRBP TAOK3 TRAF2 TUBA1A 21 interactors: DCTN1 LRRK2 MAP2K4 MAP3K4 MAP3K5 MAP3K7 MAPK1 MAPK12 MAPK13 MAPK14 MAPKAPK2 MLH1 PKN1 PLCB2 RELA SMAD7 STAT4 TAOK2 TLR3 TRAF6 ZAK
Entrez ID 120892 5608
HPRD ID 10613 03155
Ensembl ID ENSG00000188906
Uniprot IDs Q17RV3 Q5S007 A8K3Y2 P52564
PDB IDs 2ZEJ 3D6T 2Y8O 3ENM 3FME 3VN9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
autosomal  decline  difficulty  dj1  england  g2019s  gait  gu  hoehn  idiopathic  leucine  motor  movement  parkinson  pd  pigd  pink1  postural  prkn  rating  schwab  snca  society  staging  udrs  undefined  unified  updrs  yahr 
camk1  centriole  dkk1  enah  endosome  geo  gpsm2  inference  kcnq3  kpna2  lcn2  lef1  lysosome  multivesicular  nkx2  nr5a1  nup62  ontology  phosphoinositide  sfrp4  slc4a3  sort1  sstr5  stx1a  subnetwork  tbl3  transport  tshb  ube2c 
Tagcloud (Difference) ?
autosomal  decline  difficulty  dj1  england  g2019s  gait  gu  hoehn  idiopathic  leucine  motor  movement  parkinson  pd  pigd  pink1  postural  prkn  rating  schwab  snca  society  staging  udrs  undefined  unified  updrs  yahr 
camk1  centriole  dkk1  enah  endosome  geo  gpsm2  inference  kcnq3  kpna2  lcn2  lef1  lysosome  multivesicular  nkx2  nr5a1  nup62  ontology  phosphoinositide  sfrp4  slc4a3  sort1  sstr5  stx1a  subnetwork  tbl3  transport  tshb  ube2c 
Tagcloud (Intersection) ?