LRRK2 and DVL2

  • Number of citations of the paper that reports this interaction (PMID 19625296)
  • 24
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)

LRRK2

DVL2

Gene Name leucine-rich repeat kinase 2 dishevelled segment polarity protein 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 33 interactors: ACTB AKT1 ARFGAP1 ARHGEF7 BAG5 DVL1 DVL2 DVL3 EIF4EBP1 HSPD1 L3MBTL3 LRP6 MAP1B MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAPT MBP PRKCZ PTPN23 RALYL RIPK2 SH3GL1 SH3GL2 SH3GL3 STK24 STK25 STK3 STRBP TAOK3 TRAF2 TUBA1A 61 interactors: AP1M1 AP2M1 ARHGEF39 ARR3 ARRB1 ARRB2 ATN1 AXIN1 BAG3 BAHD1 CCDC33 CPSF7 CSNK1E CTBP2 DAAM1 DDI1 DPPA2 DYNLT1 ENKD1 FZD4 GABARAP GABARAPL1 ITCH LRRK2 MAP1LC3A MCRS1 OTULIN PARD6A PCBD1 PLA2G12A POLI PPM1A PRKCA PRKCB PRKCG PRPF3 RAC1 RBFOX1 RBPMS RHOA RHOXF2 RNF185 RNPS1 RUNX2 SMURF1 SNF8 SNIP1 SORBS3 TCEB3B THAP1 TIFA TP53 TRAF2 U2AF2 USP5 VANGL1 VHL ZBTB8A ZNF165 ZNF250 ZNF263
Entrez ID 120892 1856
HPRD ID 10613 03690
Ensembl ID ENSG00000188906 ENSG00000004975
Uniprot IDs Q17RV3 Q5S007 I3L2N2 O14641
PDB IDs 2ZEJ 3D6T 2REY 3CBX 3CBY 3CBZ 3CC0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
autosomal  decline  difficulty  dj1  england  g2019s  gait  gu  hoehn  idiopathic  leucine  motor  movement  parkinson  pd  pigd  pink1  postural  prkn  rating  schwab  snca  society  staging  udrs  undefined  unified  updrs  yahr 
adaptor  ap2  ap2mu2  assembled  assembles  blockage  clathrin  clustering  continuously  disassembled  dissolution  endocytic  endocytosis  follows  fz  inhibiton  internalization  lrp6  maintain  mu2  path  rab  routes  signalosome  take  transducer  transducers  vertebrates  wnt 
Tagcloud (Difference) ?
autosomal  decline  difficulty  dj1  england  g2019s  gait  gu  hoehn  idiopathic  leucine  motor  movement  parkinson  pd  pigd  pink1  postural  prkn  rating  schwab  snca  society  staging  udrs  undefined  unified  updrs  yahr 
adaptor  ap2  ap2mu2  assembled  assembles  blockage  clathrin  clustering  continuously  disassembled  dissolution  endocytic  endocytosis  follows  fz  inhibiton  internalization  lrp6  maintain  mu2  path  rab  routes  signalosome  take  transducer  transducers  vertebrates  wnt 
Tagcloud (Intersection) ?