SYNRG and APPBP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		SYNRG	APPBP2
Description		synergin gamma	amyloid beta precursor protein binding protein 2
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Membrane AP-1 Adaptor Complex Clathrin Coat Of Trans-Golgi Network Vesicle Clathrin-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Microtubule Microtubule Associated Complex Membrane Cytoplasmic Vesicle Membrane Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Microtubule Motor Activity Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Intracellular Protein Transport Endocytosis Protein Transport	Intracellular Protein Transport Protein Transport Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intracellular Transport
Pathways
Drugs
Diseases
GWAS		Lymphocyte count ( 32888494) Ovarian cancer ( 23535730) Response to angiotensin II receptor blocker therapy ( 22566498)	Interleukin-6 levels ( 33517400) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Waist-hip ratio ( 28552196)
Interacting Genes		8 interacting genes: AP1G1 AP1G2 APPBP2 CCDC91 GGA1 GGA2 GGA3 SCAMP1	122 interacting genes: - AADAC ACTN1 AHCY AIM2 AK3 ALDH1L1 ANKRD10 APP AR ARMCX5 ASCC3 ATP13A1 BCL7A BIN2 C1orf50 CALM3 CCDC167 CCDC85C CCNL1 CDK16 CHMP5 CIBAR1 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CST2 CTC1 CYBA DCD DHRS2 DHX16 DOLK DPEP1 DPYS EID3 ERO1A FAM107A FSTL1 FXYD7 GALNT3 GCSAM GP9 GPRC5C GSTP1 H2AC15 HGFAC HIPK4 HSD3B7 HSPA4 ITGB4 ITGB5 KHK KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MAN2B2 MCOLN1 MGAT4B MLLT3 MMP28 MRPL28 MSH2 MSLN MUL1 MYLK NFYA NHERF1 NPRL3 PCSK5 PEX39 PI4KAP2 PNPLA5 PPIL6 PPP1R8 PRKAA2 PRKACB PSAP PTCH1 PYROXD2 RAB7B RASSF5 RHEB RILPL1 RNF128 RNF34 RNGTT RRS1 SELENOI SELENOV SLC22A6 SLC25A23 SLC33A2 SLC7A10 SNX5 SPDYE2 SPDYE2B ST8SIA5 SYNRG SYT11 TAF11 TAFA4 TBL3 TCF25 TNP2 TRMT2A UBE2R2 UGGT2 WAS WDR24 WFIKKN1 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		11276	10513
HPRD ID		06291	05616
Ensembl ID		ENSG00000275066	ENSG00000062725
Uniprot IDs		Q9UMZ2	Q92624
PDB IDs		2MX7	8JAL 8JAQ 8JAR 8JAS 8JAU 8JAV
Enriched GO Terms of Interacting Partners?		Post-Golgi Vesicle-mediated Transport Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Trans-Golgi Network Establishment Of Localization In Cell Intracellular Protein Transport Intracellular Protein Localization Vesicle-mediated Transport Intracellular Transport Establishment Of Protein Localization To Plasma Membrane Cellular Localization Golgi To Vacuole Transport Membrane Coat Protein Localization To Cell Surface Golgi Apparatus Golgi To Plasma Membrane Protein Transport Vacuolar Transport Cytoplasmic Vesicle Membrane Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Protein Localization To Cell Periphery Golgi To Plasma Membrane Transport Clathrin-coated Vesicle Small GTPase Binding Endosome Membrane Protein Localization To Membrane Golgi To Lysosome Transport AP-1 Adaptor Complex Ubiquitin Binding Endosome Phosphatidylinositol Binding Lysosomal Transport Cytosolic Transport Clathrin Adaptor Activity Vesicle-mediated Transport To The Plasma Membrane Intracellular Vesicle Localization Within Membrane Early Endosome Membrane Membrane Protein Localization To Cilium Early Endosome Synaptic Vesicle Budding From Endosome Recycling Endosome Membrane Trans-Golgi Network Membrane Protein Transport From Ciliary Membrane To Plasma Membrane Recycling Endosome Basolateral Protein Secretion Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Lysosomal Protein Catabolic Process	Protein Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?