SYNRG and GGA2

Number of citations of the paper that reports this interaction (PMID 10747088)
94

Data Source:
HPRD (two hybrid, in vivo)

		SYNRG	GGA2
Gene Name		synergin, gamma	golgi-associated, gamma adaptin ear containing, ARF binding protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus AP-1 Adaptor Complex	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin Adaptor Complex Clathrin-coated Vesicle
	Molecular Function		Protein Binding ADP-ribosylation Factor Binding
	Biological Process	Intracellular Protein Transport Endocytosis	Intracellular Protein Transport Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730) Response to angiotensin II receptor blocker therapy ( 22566498)
Protein-Protein Interactions		8 interactors: AP1G1 AP1G2 APPBP2 CCDC91 GGA1 GGA2 GGA3 SCAMP1	30 interactors: AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC GGA1 GGA3 HGS HTT IGF2R LRP3 M6PR PIN1 RAB5A RABEP1 RABGEF1 RNF11 SORL1 SORT1 SPG21 STAB1 SYNRG TRIM23 VPS18
Entrez ID		11276	23062
HPRD ID		06291	09347
Ensembl ID		ENSG00000006114	ENSG00000103365
Uniprot IDs		A8MWU4 Q9UMZ2	Q9UJY4
PDB IDs			1MHQ
Enriched GO Terms of Interacting Partners?		Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Intracellular Protein Transport Establishment Of Localization In Cell Cellular Protein Localization Cellular Localization Vesicle-mediated Transport Transport Post-Golgi Vesicle-mediated Transport Positive Regulation Of Natural Killer Cell Degranulation Golgi To Lysosome Transport Positive Regulation Of Protein Catabolic Process Golgi To Vacuole Transport Endosome To Melanosome Transport Pigment Granule Maturation Golgi Vesicle Transport Cellular Pigment Accumulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Protein Catabolic Process Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Regulated Secretory Pathway Melanosome Organization Pigment Granule Organization Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Defense Response To Virus By Virus Positive Regulation Of Natural Killer Cell Activation Regulation Of Regulated Secretory Pathway Viral Process Lysosomal Transport Cellular Pigmentation Positive Regulation Of Exocytosis Developmental Pigmentation	Vesicle-mediated Transport Endocytosis Intracellular Transport Protein Transport Establishment Of Protein Localization Transport Establishment Of Localization In Cell Protein Localization Cellular Localization Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Lysosomal Transport Golgi Vesicle Transport Vacuolar Transport Cellular Protein Localization Endosomal Transport Regulation Of Vesicle-mediated Transport Endosome To Lysosome Transport Cytoplasmic Transport Visual Learning Membrane Organization Visual Behavior Protein Targeting To Lysosome Protein Localization To Lysosome Associative Learning Cellular Copper Ion Homeostasis Membrane Protein Ectodomain Proteolysis Signaling Protein Targeting To Vacuole Copper Ion Homeostasis Cell Communication Negative Regulation Of Signaling Establishment Of Protein Localization To Vacuole Learning Transition Metal Ion Homeostasis Membrane Protein Proteolysis Regulation Of Exocytosis Retrograde Vesicle-mediated Transport, Golgi To ER Regulation Of Synaptic Plasticity Regulation Of Protein Catabolic Process Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Phosphorylation Neural Plate Formation Negative Regulation Of Kit Signaling Pathway Positive Regulation Of Early Endosome To Recycling Endosome Transport Negative Regulation Of Tau-protein Kinase Activity Negative Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Choline O-acetyltransferase Activity
Tagcloud ?			addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true
Tagcloud (Difference) ?			addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true
Tagcloud (Intersection) ?