SYNRG and AP1G2

Number of citations of the paper that reports this interaction (PMID 10477754)
40

Data Source:
HPRD (in vitro)

		SYNRG	AP1G2
Gene Name		synergin, gamma	adaptor-related protein complex 1, gamma 2 subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus AP-1 Adaptor Complex	Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Membrane AP-1 Adaptor Complex Transport Vesicle
	Molecular Function		Protein Binding Protein Transporter Activity
	Biological Process	Intracellular Protein Transport Endocytosis	Intracellular Protein Transport Viral Process Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730) Response to angiotensin II receptor blocker therapy ( 22566498)	Sudden cardiac arrest ( 21658281)
Protein-Protein Interactions		8 interactors: AP1G1 AP1G2 APPBP2 CCDC91 GGA1 GGA2 GGA3 SCAMP1	12 interactors: AFTPH AP1S1 AP1S2 ATXN1L CENPK KDM1A NEDD4 PRMT6 RAB5A RABEP1 SYNRG XRN1
Entrez ID		11276	8906
HPRD ID		06291	04638
Ensembl ID		ENSG00000006114	ENSG00000213983
Uniprot IDs		A8MWU4 Q9UMZ2	O75843 Q86V28
PDB IDs			2E9G 2YMT 3ZHF 4BCX
Enriched GO Terms of Interacting Partners?		Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Intracellular Protein Transport Establishment Of Localization In Cell Cellular Protein Localization Cellular Localization Vesicle-mediated Transport Transport Post-Golgi Vesicle-mediated Transport Positive Regulation Of Natural Killer Cell Degranulation Golgi To Lysosome Transport Positive Regulation Of Protein Catabolic Process Golgi To Vacuole Transport Endosome To Melanosome Transport Pigment Granule Maturation Golgi Vesicle Transport Cellular Pigment Accumulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Protein Catabolic Process Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Regulated Secretory Pathway Melanosome Organization Pigment Granule Organization Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Defense Response To Virus By Virus Positive Regulation Of Natural Killer Cell Activation Regulation Of Regulated Secretory Pathway Viral Process Lysosomal Transport Cellular Pigmentation Positive Regulation Of Exocytosis Developmental Pigmentation	Protein Transport Establishment Of Protein Localization Endocytosis Protein Localization Vesicle-mediated Transport Intracellular Protein Transport Regulation Of Defense Response To Virus By Virus Viral Process Receptor Internalization Cellular Protein Localization Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Regulation Of Primitive Erythrocyte Differentiation Development Involved In Symbiotic Interaction Intracellular Transport Positive Regulation Of Stem Cell Proliferation Receptor-mediated Endocytosis Receptor Metabolic Process Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Histone H3-R2 Methylation Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Stem Cell Proliferation Receptor Internalization Involved In Canonical Wnt Signaling Pathway Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Endosome Size Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Establishment Of Localization In Cell Progesterone Receptor Signaling Pathway Chromatin Modification Regulation Of Immune System Process Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Nuclear MRNA Surveillance Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Biosynthetic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Glucocorticoid Receptor Signaling Pathway RNA Surveillance Cellular Localization Histone MRNA Catabolic Process Chromatin Organization Transport Positive Regulation Of Megakaryocyte Differentiation
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