CHEK2 and RCHY1

  • Number of citations of the paper that reports this interaction (PMID 23449389)
  • 2
  • Data Source:
  • BioGRID (enzymatic study)

CHEK2

RCHY1

Gene Name checkpoint kinase 2 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Response to tocilizumab in rheumatoid arthritis ( 22491018)
Protein-Protein Interactions 47 interactors: AATF APP ARHGAP1 ASF1A ATM ATR BRCA1 BRCA2 CDC25A CDC25C DAPK3 DBF4 E2F1 ELAVL1 ERCC6 FOXM1 KPNA2 LATS2 MDC1 MDM2 MDM4 MRC1 MSH2 MUS81 NBN NR4A1 PLK1 PLK3 POLR2L PPP2CA PPP2R2A PPP2R2B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKDC RAD9A RCHY1 REV3L RNF8 SRPK1 STRAP TP53 TSSK1B VHL 61 interactors: ADAMTSL4 AIG1 AOX1 AR ARF4 ATN1 BIRC3 C19orf80 CAMK2A CAMK2G CDK9 CDKN1B CHD8 CHEK2 COPE COX6C CYBA DCUN1D5 F7 FADS6 GFI1B GORAB HRG KAT5 KLHL41 KRTAP9-2 LIMS2 MDM2 MEOX2 MSH3 MT2A NKD2 NLK NOTCH2NL PGLS PLAGL2 PMM1 PRDX4 RAB11A RBM38 RILP RPLP1 RPN2 SEMA4C SERPINA1 SERPINA5 SERTAD1 SRPRB TAOK2 TMBIM1 TMEM14C TMEM184A TP53 TP63 TP73 TRIM8 UBASH3B UBE2D2 UBE2D4 WDR74 ZNF160
Entrez ID 11200 25898
HPRD ID 05084 07607
Ensembl ID ENSG00000183765 ENSG00000163743
Uniprot IDs O96017 C7E542 E7EMC8 E7ETW5 J3KPI0 Q96PM5
PDB IDs 1GXC 2CN5 2CN8 2W0J 2W7X 2WTC 2WTD 2WTI 2WTJ 2XBJ 2XK9 2XM8 2XM9 2YCF 2YCQ 2YCR 2YCS 2YIQ 2YIR 2YIT 3I6U 3I6W 3VA4 4A9R 4A9S 4A9T 4A9U 4BDA 4BDB 4BDC 4BDD 4BDE 4BDF 4BDG 4BDH 4BDI 4BDJ 4BDK 2JRJ 2K2C 2K2D
Enriched GO Terms of Interacting Partners?
Tagcloud ?
alleles  atm  brca1  brca2  brip1  cdh1  confer  contributing  contributive  fashion  hereditary  influences  lifetime  offers  otherwise  palb2  penetrance  penetrant  personal  polygenic  predisposing  predisposition  quite  snp  stk11  suggestive  suspicion  unlikely  venue 
20s  alters  animal  conserved  correlatively  crucial  degradation  display  e3  establish  handful  homeodomain  hox  hoxa2  interacts  ligase  modes  multitude  pirh2  promotes  proteasomal  proteasome  regulators  reports  reveal  stabilization  subunits  ubiquitin  ubiquitination 
Tagcloud (Difference) ?
alleles  atm  brca1  brca2  brip1  cdh1  confer  contributing  contributive  fashion  hereditary  influences  lifetime  offers  otherwise  palb2  penetrance  penetrant  personal  polygenic  predisposing  predisposition  quite  snp  stk11  suggestive  suspicion  unlikely  venue 
20s  alters  animal  conserved  correlatively  crucial  degradation  display  e3  establish  handful  homeodomain  hox  hoxa2  interacts  ligase  modes  multitude  pirh2  promotes  proteasomal  proteasome  regulators  reports  reveal  stabilization  subunits  ubiquitin  ubiquitination 
Tagcloud (Intersection) ?